Online Now: The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks dlvr.it/TLZkmH

New study reveals that vimentin plays a crucial role in DNA #repair and lipolysis. Depleting vimentin leads to DNA #damage and impairs repair mechanisms. nature.com/articles/s4138…

Find the housekeeping genes for your qPCR ACTB, B2M, GAPD, HMBS, HPRT1, RPL13A, SDHA, TBP, UBC, YWHAZ "internal control gene-stability measure M as the average pairwise variation of a particular gene with all other control genes" "we recommend the minimal use of the three most

Why do wounds in the mouth heal without scars? New work in Science Translational Medicine shows that oral fibroblasts suppress fibrosis through the proteins AXL and GAS6, and finds stimulating AXL recapitulates these benefits in facial skin wounds in mice. scim.ag/46xnJ3t

Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published theguardian.com/science/2025/j…

1/11 Our study on subclonal immune evasion in non-small cell lung cancer has just been published in Cancer Cell cell.com/cancer-cell/fu…

.Anoop Kumar Yadav, Jadhav, Jakub Svenda, Hana Sedlackova et al. present a novel cell-permeable biotin-HaloTag ligand. The reported ligand enables in vivo labeling & provides capabilities for efficient affinity capture of protein variants from live cells. hubs.la/Q03xv9Sd0

The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets dlvr.it/TLyB5j

Researchers have claimed that the number of redundancies being made in UK higher education could be much higher than previously thought, potentially impacting more than 20,000 jobs timeshighereducation.com/news/universit…

📢 For all HaloTag lovers💙💚💛❤️💜🩶 we are excited to share that our work, in which we developed a new biotin-HaloTag ligand, is now published in Journal of Cell Biology! Full link here: rupress.org/jcb/article-ab…

Predicting the translation efficiency of messenger RNA in mammalian cells. #TranslationEfficiency #TranslationalControl Nature Biotechnology nature.com/articles/s4158…

I wrote an end-to-end tutorial to replicate this genomics figure during the last winter holidays 👇 Take a look at the website and follow the step-by-step guide here crazyhottommy.github.io/reproduce_geno…

A lack of career progression within UK universities is “demoralising” staff and threatening to push people out of the sector, as institutions respond to the financial crisis by freezing promotions and concentrating hiring on lower-level positions timeshighereducation.com/news/staff-dem…

Mechanotransduction in the nucleus Multiple TFs transmit mechanical forces into transcriptional regulation. Nuclear shape, size, and chromatin abnormalities are common features of many diseases.

Matrix-induced nuclear remodeling and mechano-therapeutics dlvr.it/TMgmjj

I am delighted to share this new review in Nature Cancer that I co-author with Anqi Dong In which we discuss the different EMT tumor states and their implications for metastasis and cancer therapy.

Now out in its final form, with a new title "Mechanical control of cell fate decisions in the skin epidermis" and simulations/quantifications! See below for thread of how unbalanced tensions can bias fate choices in minimal 3D models of tissues/tumors! nature.com/articles/s4146…

Syndromic epidermal differentiation disorders: a new classification toward pathogenesis-based therapy The authors present a new gene- and protein product function-based classification for the group of disorders formerly called ichthyosis. Read more: doi.org/10.1093/bjd/lj…

Our RAEFISH spatial transcriptomics technology is now published in Cell Cell! RAEFISH enables sequencing-free whole genome spatial transcriptomics at single molecule resolution. This work represents the first time that transcripts from more than 23,000 genes were

Mapping cryptic phosphorylation sites in the human proteome | The EMBO Journal embopress.org/doi/full/10.10…