#PressRelease 📰 Australian researchers have discovered that multiple chemicals found in cigarette smoke & e-cigarettes alter the function of a key type of immune cell found in the lungs. In our News Release: hubs.la/Q032-6GS0 Original paper in JEM: hubs.la/Q032Z_330

In Journal of Experimental Medicine, Wael Awad, Mayal, Xu, Hansbro Research Prof. Jamie Rossjohn et al show that cigarette smoke contains a diverse mix of chemicals that bind the antigen-presenting protein MR1 and modulate MAIT cell function in the lung through diverse mechanisms. hubs.la/Q032_vzP0

.Wael Awad, Mayal, Xu, Hansbro Research Prof. Jamie Rossjohn et al. Monash University show that cigarette smoke contains a diverse mix of chemicals that bind the antigen-presenting protein MR1 and modulate MAIT cell function in the lung through diverse mechanisms. hubs.la/Q032_4f90

Have you been thinking about trying vapes or e-cigarettes? Think again! Most e-cigarettes contain nicotine and other harmful substances. Some products claiming to be nicotine-free have been found to contain nicotine. Nicotine is highly addictive and has damaging effects on the

Cigarette smoke chemicals bind MR1 and modulate MAIT cell function in the lung through diverse mechanisms, impacting their ability to respond to respiratory infections and potentially contributing to disease Journal of Experimental Medicine Rossjohn lab Jemma Mayall Wael Awad doi.org/10.1084/jem.20…

Cigarette smoke alters immune cell function in the lungs news-medical.net/news/20250117/…

How Cigarette Smoke Cripples Key Lung Defenders medindia.net/news/how-cigar…

Cigarette Smoke Impairs Lung Immune Cells, Elevates Infection Risk karmactive.com/cigarette-smok… via karmactive

Cigarette smoke components modulate the MR1–MAIT axis, say Wael Awad (Wael Awad), Jemma Mayall, Weijun Xu, Jamie Rossjohn (Prof. Jamie Rossjohn) and colleagues Monash University: hubs.la/Q032_dm50 #COPD

Cigarette smoke components harm MAIT cell function, increasing infection risk and exacerbating diseases like chronic obstructive pulmonary disease. by Awad W, Mayall JR (...) Rossjohn J et 22 al. in J Exp Med rupress.org/jem/article/22… #MedX #MedResearch

.Wael Awad, Mayal, Xu, Hansbro Research Prof. Jamie Rossjohn et al. Monash University show that cigarette smoke can impair MAIT cell function by diverse mechanisms, and potentially contribute to infection susceptibility and disease exacerbations. hubs.la/Q032-_qw0 #MucosalImmunology

Happy to share our latest findings out today in PNASNews by Caroline Boulouis showing how human mucosal-associated invariant T (#MAIT) cells rapidly adapt their functional response profile to cues in the microenvironment pnas.org/doi/10.1073/pn… Karolinska Institutet Center for Infectious Medicine #immunology

Happy to share our #MAIT lab Tsinghua SIGS latest review on our favourite cell homing in intestinal homeostasis and inflammation! Science Advances science.org/doi/10.1126/sc…

🔓Now on Peeref: Cigarette smoke components modulate the MR1–MAIT axis 🔗: peeref.com/works/84832697 👁️: Altmetric: 314 Wael Awad Jemma Mayall Hansbro Research Prof. Jamie Rossjohn Journal of Experimental Medicine Rockefeller U. Press

Commentary Cancer Cell Ton Schumacher Lab Learning the language of T cell receptors through large-scale screening cell.com/cancer-cell/fu…

Our recent review on MR1/MAIT axis Molecular Insights Into MR1‐Mediated T Cell Immunity: Lessons Learned and Unanswered Questions onlinelibrary.wiley.com/doi/10.1111/im… Prof. Jamie Rossjohn Prof. Jamie Rossjohn Monash Medicine, Nursing and Health Sciences

Mitochondria produce nucleobase ligands for T cells. Our recent paper was published today in PNAS. Prof. Jamie Rossjohn Prof. Jamie Rossjohn Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells pnas.org/doi/10.1073/pn…