We’re presenting AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 It could help scientists better understand how biological systems function, save time in research, advance drug design and more. 🧵 dpmd.ai/3XuMqbX

How I woke up one day and decided to solve a math conjecture from the 1970s ⤵️

The age of Neural Engineering is here... and Max Hodak's Science Corp is on the frontier: ‣ Curing blindness ‣ Merging mind & machine with BCIs ‣ Today, revealing a new kind of neural probe ‣ And exploring consciousness itself on Episode 65 of S3.

I had an idea in college which I've long thought could be, in many ways, the ultimate BCI technology. What if instead of using electrodes, we used biological neurons embedded in electronics to communicate with the brain? Enter biohybrid neural interfaces: science.xyz/news/biohybrid…

today, i'm excited to release a reinforcement learning guide that carefully explains the intuition and implementation details behind every single fundamental algorithm in the field. enjoy :) naklecha.com/reinforcement-…

Gödel's incompleteness theorem and the Copenhagen interpretation of quantum mechanics have had devastating effects on the epistemology of people who don't fully understand them; exposure to these ideas should require a security clearance

Keep thinking.

let life ripen & then fall; Will is not the way at all

shoutout to jhana 3, one of my fav jhanas fr

What if bigger models are actually more interpretable? Mixture of Experts (MoE) have become central to scaling LLMs and are used in nearly every frontier model. Yet we still lack a mechanistic understanding of how MoEs represent features differently than dense models. How do

Can ultrasound make you smell things that aren’t there? Turns out, yes! We reliably triggered distinct scents like a campfire burn or a garbage truck by targeting our brains with ultrasound. To our knowledge, this has never been done before, even in animals. This may be a

you need to be setting up your christmas tree in the sierras during a blizzard

one of the best introductory write ups on the topic by far, highly recommended

Announcing Flapping Airplanes! We’ve raised $180M from GV, Sequoia, and Index to assemble a new guard in AI: one that imagines a world where models can think at human level without ingesting half the internet.

New Paper! RL can teach our models to solve math or code, but open-ended tasks — which make verification expensive or even impossible — remain difficult to optimize. LLMs-as-Judges help, but often struggle to retrieve information even when it is present. Reinforcement Learning