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Long overdue:our study showing concomitant scalp and limb cooling is safe and tolerable in patients using cryotherapy to prevent hair loss and neuropathy during chemotherapy. Important data supporting the phase 3 trial ongoing! link.springer.com/article/10.100… Paxman Aishwarya Bandla

Shifting focus to B-cells in gastric cancer: Our study examines multiple cohorts and employs spatial profiling. This provides fresh insights into the tumor microenvironment, complementing T-cell focused studies of the TME link.springer.com/article/10.100… Ryan Yong Kiat Tay Joseph J Zhao

Just published JAMA with Sam Klempner and Jeeyun Lee MD jamanetwork.com/journals/jama/… Our Editorial on GEMSTONE-303 with sugemalimab and chemo. Key takeaway: PD-L1 inhibition shows similar efficacy to PD-1. More options for patients, but no clear advantage over existing treatments.

Mattehorn study showed EFS improvement and strong OS trend with FLOT+duravalumab. Great news to establish the global standard for fit patients with locally advanced gastric/GEJ cancer. Looking forward to the detail.OncoAlert OncoDaily astrazeneca.com/media-centre/p…

Excited to share biomarker analysis of CM649 Nature Medicine Yelena Y. Janjigian MD Nivo benefit was enriched in TMB-H> EBV and GS > CIN. Targeted tx is needed for CIN. Nivo+Ipi benefit was seen in Treg↑ (FOXP3+CCR8), supporting Treg or CCR8 targeting tx in GC. nature.com/articles/s4159…

From the April issue:Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution brnw.ch/21wRND9 By Haoran Ma, Supriya Srivastava, Raghav Sundar, Patrick Tan, and colleagues Duke-NUS Medical School NUS A*STAR Genome Institute of Singapore (A*STAR GIS)

Honored to give the Keynote lecture at the Sixth Annual Paul R. O’Hara Esophagogastric Symposium in the University of Colorado Cancer Center. Sharing our work in gastroesophageal cancer and peritoneal metastases. Many thanks to Sunnie Kim, MD for inviting me to speak!

Thursday, April 24 at 6pm, Raghav Sundar will moderate the next Center for Gastrointestinal Cancers CME Webinar spotlighting #GastroesophagealCancers. Join for presentations + discussion from Drs. Daniel Boffa, @yalesurgery, Kevin Du, and Dr.JoannaGibson. ➡️Register: bit.ly/4jRXby5

This afternoon starting at 2pm CDT, Drs. Barbara Burtness, Moein Rajaei, PhD, Jeffrey Townsend, Longgang Zhao, and Raghav Sundar present research during the first poster session of #AACR25. Smilow Cancer Hospital Yale School of Medicine Yale New Haven Hosp Yale Nursing

Excited to be in Chicago for #AACR25! Feels a little surreal to be at McCormick but not for ASCO! Looking forward to listening to some amazing science and breakthroughs in cancer biology and therapeutics. Sam Klempner Joseph J Zhao

Read more about #AACR25 speaker Raghav Sundar's efforts to chart gastric cancer evolution through tumor ecosystems and metastatic pathways in this Cancer Discovery paper from this month's issue doi.org/10.1158/2159-8…

.Raghav Sundar shares how spatial heterogeneity is driven to an evolution over space and time in #gastriccancer. As the tumor morphs, so does the TME, warranting different considerations in treatment based on heterogeneity differences. #AACR25 Center for Gastrointestinal Cancers Smilow Cancer Hospital

Grateful to be given the opportunity to share our work on tumor evolution in gastric cancer and peritoneal metastases at #AACR25 with Dr Sun Young Rha Sam Klempner Joseph J Zhao Choong-kun Lee, MD, PhD

Published today simultaneously with #AACR25 our work on colorectal cancer peritoneal metastases in Clinical Cancer Research. aacrjournals.org/clincancerres/… slowly heading toward the goal of treating this difficult disease with novel therapeutics

String of #AACR25 posts coming up! Proud of the work by Joseph J Zhao unraveling epigenetic mechanisms of peritoneal metastases in gastroesophageal cancers. Sam Klempner Ong Chin-Ann Johnny

Thrilled to share our latest Review on Gastric Cancer in the The Lancet covering the latest in the treatment and management of this illness Lizzy Smyth Kohei shitara Hanneke van Laarhoven Sheraz Markar Yelena Y. Janjigian MD & Izuma Nakayama. thelancet.com/journals/lance…

Cancer patients with B cell malignancies and differential expression of CD24, CDK14 and PLEKHG1 have highest risk of breakthrough infections after SARS-CoV2 vaccination nature.com/articles/s4154… Thank you Kuan Rong Chan Raghav Sundar for the collaboration! 😎

📢It's #ESMO election time! I am delighted to be nominated for ESMO Director of Education 😊 ALL the nominees are fantastic representing the global ESMO - Eur. Oncology community 🌍 🙏for all the good wishes Rules this year for social media so that's it from me! Now please vote 🗳️

A tribute to Dr. Agatsuma was a meaningful moment during my DESTINY-Gastric04 presentation at #ASCO25 with NEJM publication. I deeply respect him and the entire team behind the development of T-DXd. ASCO OncoAlert Daiichi Sankyo Daiichi Sankyo US AstraZeneca Oncology at AstraZeneca

Gastric cancer The Lancet doi.org/10.1016/S0140-… 👏Excellent and comprehensive summary from screening to targeted therapies by Raghav Sundar Lizzy Smyth Yelena Y. Janjigian MD Kohei shitara Hanneke van Laarhoven ESMO - Eur. Oncology