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Lively discussions and strong science in Porto GEDII 💯

Reflecting back, GEDII congress last week was great for science, beautiful Porto, friends and.. Portuguese on-plate nutritional support which I never saw before...😄 alessandro armuzzi Manuel Barreiro Fernando Magro Paulo G. Kotze #GlenDoherty

Kudo to Jami Kinnucan, MD, FACG, AGAF, FCCF for highlighting this topic of integrative medicine in IBD. Another step forward in addressing pts' interest in these options and potential benefit in combinations thru an evidence-based approach....

Capsule endoscopy is making its slow but sure way into clinics for monitoring Crohn and identifying the pts that will benefit from T2T approach. If you're in #ECCO2025 come tomorrow to hear on this and more in Medtronic symposium on our CURE-CD trial results

Our RCT now in Gastroenterology : Pts with #Crohn in remission, who recieved treat-to-target Tx guided by #capsule endoscopy inflammatory assessment, had a significantly lower flare risk over 24m compared to pts continuing standard care Helmsley Charitable Trust gastrojournal.org/article/S0016-…

Extended Risa induction IV 1200mg/4w is no better than SC 360mg/8w (<1/10th the drug exposure) A quintessential study by Remo Panaccione, MD, FRCPC to indirectly suggest previously found association of low Risa levels and low response rate do not imply causality pubmed.ncbi.nlm.nih.gov/39909280/

Dogma-challenging 🇦🇺RCT in roypounder.apt : No harmful effect in active CD of #diet enriched by 3 emulsifiers (incriminated by pre-clinucal data). Small trial, but sits well with benefits of EEN, despite high emulsifier content of formulas. Search goes on... onlinelibrary.wiley.com/doi/10.1111/ap…

Just saw pt with isolated persistent (7y) complex perianal fistula without any luminal CD, similar to nice series by @Dr. Samir A Shah and Hannah Fiske Goodrich, MD in IBDJournal & CC360 A unique CD subset or a complicated cryptoglandular? To aTNF or not ? Still no answer pubmed.ncbi.nlm.nih.gov/39679162/

Small bowel inflammation proximal to ileocolonoscopy reach is important factor for prediction of long-term outcome in #Crohn ! Can be determined by DBE as in this nice study from 🇯🇵, or by #capsule-endoscopy

A sub-study of CURE-CD trial: No benefit (=no need) of bowel preparation for SB #capsule-endocopy in CD pts, when each pt compared to him/herself (with/without prep). Supports similar studies comparing different pt groups. המרכז הרפואי שיבא pubmed.ncbi.nlm.nih.gov/40176636

Still limited number, but reassuring important data on safety of Rota vaccine in bio-exposed newborns

Clever pragmatic T2T trial. Looking forward to results.

Noting my COI, it' s personally really moving for me to recieve such heartwarming messages from pts in Spain treated with #CurQD. Grateful to our partner-friends there Naturcyte who facilitated this.

Seminal work by Siew Ng & Gil Kaplan MD MPH on global IBD evolution over a century. Intriguingly echoing similar patterns in #asthma Should we start calling IBD 'Allergic-immune disease' ? Or are we satisfied with 'Toxicogenic barrier disruption' ? Either way, environment rules

Interesting angle on AhR avtivation by indole derivatives for maintaining barrier integrity and ameliorating IBD

Welcome to Dr Nir Salomon as our guest at the The Hospital for Sick Children (SickKids) 2025 Division of Gastroenterology, Hepatology and Nutrition Research Day. Nir is speaking about the development of CurQD as an example of new neutraceuticals as a treatment option for IBD.

As noted in this paper, we dont give prep to SB capsule. Unwarranted, and turns a pt-friendly procedure into much less so

Nice case report from Netanel Krugliak and Dr Mark Silverberg in Toronto, on use of #CurQD for a #Crohn patient who flared after having to stop IFX due to dilated cardiomyopathy University of Toronto My COI of note share.google/VCZMzZp6dJicyZ…

💯 Thank u for sharing ! Really moving to hear. Wish u best of health

‼️Anyone interested in organ fibrosis please join us for the Keystone Fibrosis Symposium 2026 ‘Cross Organ Pathology and Pathways to Clinical Development’ ‼️Introduction video can be found here url.avanan.click/v2/r01/___http…. Registration 👉🏻 keysym.us/KSFibrosis26 Suzanne Devkota