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Happy to have contributed to 1st #CRISPR prime editing in primary human T cells, using RNPs. Great collaboration of Joanna Yeh J. Keith Joung Dr Marcela Maus Luca Pinello labs out now Nature Biotechnology. Excited to see how PE will boost #celltherapy in the future! nature.com/articles/s4158…

Our department held a pumpkin carving contest yesterday and some members of the The Joung Lab won with this pumpkin! I have to admit that my face on a pumpkin is not something I ever imagined I would see...! 😂(Thanks to Regan Szalay for the pictures.)

Said “see you later” to one of my favorite people on the planet. I couldn’t have asked for a better mentor and friend to learn from over the past year and a half. Munich is lucky to have you! When I grow up, I want to be just like you, @JulesGrunewald .

Regan Szalay Thanks so much, Regan. It was so wonderful to work with you and I’m so proud of you!! breathtaking to watch how you became such a brilliant young scientist! See you soon in Munich Regan Szalay BOS —> MUC :)

@JulesGrunewald thanks for all of your amazing contributions (scientific and non-scientific) over the past 5 years! You will be missed by all of us (but esp. by Regan Szalay and Eliza Jane Holtz). Our work together will continue and I know you will go on to do amazing things.

The Joung Lab J. Keith Joung Last but not least, I want to highlight some hyper-talented colleagues & friends that I’ve worked with over the last 4 years: @Ollie_Ray_ 🧬 Ronghao Zhou 🧬 Bret Miller 🧬 @lm_langner 🧬 Regan Szalay 🧬 Eliza Jane Holtz -- You are 100% fantastic...

The Joung Lab J. Keith Joung @Ollie_Ray_ Ronghao Zhou @lm_langner Regan Szalay Eliza Jane Holtz … and I am so thankful for all your brilliant work & the fun we had together in the lab! I learned so much from y’all and I miss you tremendously. Please visit us over here! See you soon ♥

Was great to finally (after a ~2.5 year hiatus) have the The Joung Lab gather in person on Monday night for our annual summer party. Had a wonderful dinner at Davio's in the Seaport with both current and previous lab members. Thanks to Dylan for organizing this memorable event! (1/3)

More photos...(2/3)

Group photo...(3/3)

Fun dinner yesterday with The Joung Lab members Eliza Jane Holtz @ivy_thuy_nguyen Justine Y Shih, Ken Lam, Ravi Bajpai, and Regan Szalay on the last evening of the #ASGCT22 annual meeting. It was nice that Julian Grünewald could also join us!

Was a special weekend, getting to finally celebrate the College of Wooster Class of 2020! So great to catch up with 3/5 of my IS students, each doing wonderful things post-CoW! #proudadvisor Pictured: @leman_simpson Regan Szalay, and Matthew Mahoney-White

Great first CRISPR technology session at #CRISPR2022! Novel next gen synthetic base editors by Nicole M. Gaudelli /Beam Therapeutics, recording of transcriptional histories using spacer acquisition by Randall Platt, and finally improved prime editing by Regan Szalay

It's not every day you come to work and find a groundhog in the fume hood! Critter came in through the ceiling and dropped in. Thank you College of Wooster Facilities crew for the prompt, humane eviction.

As Beam recently has revealed more details of its future development plan for sickle cell disease (SCD), it is a good time to review the current status and predict the future landscape of treating SCD with CTX001 using CRISPR/Cas9 and BEAM-101/102 using ABE.

Boston RT party!🧬So excited about our #CRISPR prime editing work, out Nature Biotechnology today – great The Joung Lab team work w/ Bret Miller, Regan Szalay, @johnASeed1, Chris Woodilla, Eliza Jane Holtz, Karl Petri & J. Keith Joung nature.com/articles/s4158…

Engineered CRISPR prime editors with compact, untethered reverse transcriptases go.nature.com/3SCy1Fw

Excited that the latest The Joung Lab paper describing split #CRISPR prime editors is out online Nature Biotechnology today. This work was led by Julian Grünewald, Bret Miller, Regan Szalay with co-authors Peter Cabeceiras, Chris Woodilla Eliza Jane Holtz Karl Petri nature.com/articles/s4158… 1/7

Today in bioRxiv, we describe the varied durability of epigenetic editing in the context of cardiovascular disease target genes (hPCSK9, hANGPTL3, and hAGT). biorxiv.org/content/10.110…