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NEW 🔥🔥#CID Brad Spellberg A simple diagnostic ASP ⛔ routine ordering of urine cultures using education, audit&feedback➕ hospital-wide screensaver👇 ⬇️ inpatient U. Cx orders(~-50%) & rates of hospital CAUTIs w/o change in hospital mortality #IDtwitter academic.oup.com/cid/advance-ar…

Who's ready to take a deep dive into SURMOUNT-1 by Ania M. Jastreboff, MD, PhD Dr. Louis Aronne NEJM evaluating @lillypad's tirzepatide for #obesity? Here are interesting particulars I pulled from the manuscript and appendix, as compared to Wegovy's STEP-1: 1/

#SURMOUNT-1 trial 👉 Tirzepatide Once Weekly for the Treatment of Obesity ⏰ 72-week 💉5 mg, 10 mg, or 15 mg of tirzepatide once weekly 📌 change in weight ⤵️−15.0% with 5-mg ⤵️−19.5% ⤵️−20.9% with 15-mg doses

Nice supplement relating to noon conference today. Thanks to Dan Reynolds, MD for a great talk!

Excellent and hopefully well seen piece in JACC Journals #JACCHeartFailure on GDMT in HFrEF Thoughts on the differences between groups? Getting on even three agents looks pretty good! #FunctionNotFailure jacc.org/doi/abs/10.101…

Nice review of non-inferiority trials. Thanks to Alexa Loncharich for presenting the Caravaggio trial! @WashUIMRes

ICU Infectious Disease Pearls and Pet Peeves: I love ID (or at least I did until COVID-19 came into our lives…) and for quite some time I wanted to write a relevant thread. These are some of the simple things that I always try to keep in mind and discuss/apply during rounds:

Need another reason to love St. Louis? Whether you’re driving, using public transportation or biking, commuting here is a breeze – especially compared to increasingly congested major cities. Full video here: youtu.be/cbhnHlE7UpE

Excited for journal club tomorrow w Rahul Peravali where we’ll about the results of the SURMOUNT-1 trial @WashUIMRes

quick thread on the BOX trial and how my thinking about Bp following cardiac arrest has evolved over time... in other words why I was wrong... 🧵

Door to prednisone time for alcohol-associated hepatitis... doesnt matter Take your time. Rule out infection. Sit down and hammer out a plan for the AUD. Feed the patient. #livertwitter

Join us for a great case discussion! Clinical reasoning to the max with Dr. Sonia Godbole and Dr. Blinder. Tomorrow. High noon. @WashUHeme @WashUIMRes Test Account @WUHemeOncFellow

Very excited for Dr. Alan Braverman’s presentation at @WUDeptMedicine CPC tomorrow!

DOM Grand Rounds this Thursday. 8am. Clopton. Learn about amyloidosis, meet new colleagues, and eat kolaches!

Ultrasound: “no evidence of cholecystitis” Op report: “gangrenous cholecystitis with extremely friable tissue. Purulent drainage with manipulation of gallbladder.” I've seen this many times. Thread 1/

Come one, come all to Solid Organ Transplant Day at Medicine Grand Rounds! Thursday. 8am. Clopton.

#echofirst image for trainees / fellows (not for experienced docs! 😃) Acute chest pain admission - bedside POCUS in ED 1) What do you see? 2) What is your top differential diagnosis? 3) What would you do next? 4) What urgent intervention does this patient need? American Society of Echocardiography #ACCFIT

Looking forward to a great Medicine Grand Rounds this week!

I did not expect this piece to resonate with so many people. This is dedicated to all the clinicians in the trenches. thelancet.com/journals/lanha…

Really nice review of HFpEF in JACC Journals Amazing how far we've come in the last 10 years! jacc.org/doi/epdf/10.10…