Hanna Tukachinsky
@htukachinsky
Translational scientist at Foundation Medicine | Boston by Foot tour guide as a side hobby | Opinions my own
ID: 1412820880145719297
07-07-2021 17:08:50
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👀 Check out what’s popular this week in #JCOPO: Tumor Fraction Correlates With Detection of Actionable Variants Across > 23,000 Circulating Tumor DNA Samples 👉 fal.cn/3t8RC Hatim Husain Geoff Oxnard MD #ctDNA #lcsm
Unique spectrum of BRAF alts in prostate cancer! 👉3% BRAF activated, mostly rearrangements and K601E. 👉Diverse BRAF fusions detected both in tissue DNA (F1CDx) and liquid ctDNA (F1LCDx). Love the teamwork here!🙌 Neeraj Agarwal, MD, FASCO Sumanta K. Pal, MD, FASCO Emmanuel Antonarakis Hanna Tukachinsky
Beautiful summary of mCRPC treatment options with recommended algorithms by silke gillessen #GU23
Thought-provoking commentary "Alpelisib Efficacy without Cherry-PI3King Mutations" on our paper with Hope Rugo and Geoff Oxnard MD in current CCR issue #breastcancer Foundation Medicine
Bravo Joel W. Neal, MD, PhD , love this paradigm Charu Aggarwal, MD, MPH, FASCO has championed: early LBx 🩸🧬 based on a *clinical diagnosis* of lung cancer, in parallel to pathologic diagnosis🔬!
Geoff Oxnard MD Vivek Subbiah, MD Relay Therapeutics Brenton Mar I recently heard that ALL the 3 phase-3 trials continue to have very slow accrual🚶♀️. 2 have shut down due to slow accrual! Took these companies a long time to realize that you could enroll ctDNA➕. 1/3rd of cholangio; not enough tissue for NGS. 💡🩸 can fill the void.#ASCO23
Thank you Alex Chehrazi-Raffle, MD et al. for collaborating on this important work about BRAF beyond V600E (mutations and fusions): an exciting, potentially targetable biomarker that has been largely overlooked in #prostatecancer.
🎉 My first paper in JLB International Society of Liquid Biopsy! 🤓 A pleasure to collaborate with SCRUM-Japan to describe pan-tumor bTMB 🩸concordance w TMB 🔬& identification of cancer pts w better outcomes on IO: sciencedirect.com/science/articl…
Just published Clinical Cancer Research Is it a myth🐉that you can’t detect fusions on #ctDNA? 👇🏾Presenting one of the largest datasets on #LiquidBiopsies & Fusion🖇️detection 53,842 patients 1️⃣4️⃣% had a pathogenic rearrangement detected Shedding💦matters OncoAlert aacrjournals.org/clincancerres/…