The Martinez-Rivera Lab's website is now available! Pls share! :) 🎉 martinezriveralab.org

Learning produces an orthogonalized state machine in the hippocampus nature.com/articles/s4158…

Multi-level encoding of reward, effort, and choice across the frontal cortex and basal ganglia during cost-benefit decision-making cell.com/cell-reports/f…

Proactive and reactive construction of memory-based preferences nature.com/articles/s4146…

Medial orbitofrontal, prefrontal and amygdalar circuits support dissociable component processes of risk/reward decision making jneurosci.org/content/early/…

During foraging with reward-threat conflicts in mice, #dopamine modulates two competing neuron types in the striatum for flexible threat-coping, from initial threat avoidance to eventual overcoming of the threat nature.com/articles/s4159…

Communications Biology Devaluing memories of reward: a case for dopamine nature.com/articles/s4200…

Our manuscript studying transcriptional patterns of cocaine Withdrawal vs. Extinction is now available! Nature Communications. Leanne Angélica Minier Toribio Caleb Browne Philipp Mews Eric J. Nestler, MD, PhD Friedman Brain Institute 👇🏽👇🏽 nature.com/articles/s4146…

Nature Neuroscience Prospective contingency explains behavior and dopamine signals during associative learning nature.com/articles/s4159…

The Geometry of Concepts: Sparse Autoencoder Feature Structure. arxiv.org/abs/2410.19750

Hippocampal and thalamic afferents form distinct synaptic microcircuits in the mouse infralimbic frontal cortex: Cell Reports cell.com/cell-reports/f…

𝗛𝗼𝘄 𝘀𝗵𝗼𝘂𝗹𝗱 𝘄𝗲 𝗱𝗲𝘁𝗲𝗿𝗺𝗶𝗻𝗲 𝗮 𝗯𝗿𝗮𝗶𝗻 𝗿𝗲𝗴𝗶𝗼𝗻'𝘀 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝗰𝗲? We introduce "importance" in terms of extent to which a region's signals steer/contribute to brain dynamics as a function of brain state Work by Joyneel elifesciences.org/reviewed-prepr…

Parallel processing of past and future memories through reactivation and synaptic plasticity mechanisms during sleep nature.com/articles/s4146…

Nat. Commun.: Probabilistic alignment of multiple networks nature.com/articles/s4146…

From avoidance to new action: the multifaceted role of the striatal indirect pathway nature.com/articles/s4158…

Congrats to Pingping Zhao in the lab for publishing this very useful protocol paper on GRIN lens implantation strategies journals.plos.org/plosone/articl…

I’m excited to share a new paper from the lab. The study led by Xiaowei Gu reveals how the mPFC encodes complex emotional memories, using an internal model to infer emotional associations and memories via projections to the amygdala rdcu.be/el19t nature.com/articles/s4158…

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j3xGs8

Nat. Neurosci.: Resilient cortical maps nature.com/articles/s4159…

Nature Neuroscience What dopamine teaches depends on what the brain believes nature.com/articles/s4159…