Delighted to announce an extension of Development involvement with Review Commons As a trial Development editors will help coordinate peer review of Review Commons submissions We hope it encourages more dev biologists to try out Review Commons reviewcommons.org/blog/developme…

We are excited to launch pilot with The Company of Biologists for more efficient #PreprintReview. Editors from Development and J Cell Science join forces and will participate in coordinating the peer review on behalf of Review Commons in the fields of development and cell biology.

Congratulations to Julio Saez-Rodriguez Saez-Rodriguez Group on becoming the new head of research of EMBL-EBI and congratulations to Jo McEntyre for the promotion to Deputy Director of EMBL-EBI. ebi.ac.uk/about/news/ann…

We welcome Julio Saez-Rodriguez Julio Saez-Rodriguez as our new Head of Research! Associate Director for EMBL-EBI Services Jo McEntyre Jo McEntyre has been promoted to Deputy Director of EMBL-EBI & Rolf Apweiler is stepping back to Associate Director as he looks towards retirement.

Introducing Genie 2, our latest protein design model! Genie 2 sets a new state of the art on key design metrics and supports motif scaffolding, including that of multiple motifs with undefined geometric relationships, a feature new to protein diffusion models. (1/5)

My thesis develops 3 capabilities necessary for AI-driven cell engineering: Universal cell representation Perturbation effect prediction Closed-loop experiment design The goal is a 'virtual cell' that augments hypothesis-driven lab experiments with in-silico experimentation.

What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design

Blaise Agüera (@blaiseaguera.bsky.social) Our conversation is inspired by this new paper from Blaise and collaborators, demonstrating the spontaneous appearance of self-replicating computer code from an initially random assortment. With obvious implications for the origin of life. arxiv.org/abs/2406.19108

Read the interview by Thomas Lemberger Thomas Lemberger with Michael Bronstein Michael Bronstein #DeepMind professor of #AI University of Oxford. AI-driven biology: rethinking experiments and computation: embopress.org/doi/full/10.10… And watch the related podcast here: youtube.com/watch?v=F4x5GC…

The Review Commons team is visiting Rome! 28 Nov: La Sapienza Universita di Roma Sapienza Università di Roma 29 Nov: @EMBL Rome Meet Project Leader Thomas Lemberger & Managing Editor Sara Monaco to discuss preprint peer review and more!

Thanks to EMBL Rome for hosting Sara Monaco and Thomas Lemberger for a full day event on open science and innovations in scientific publishing.

At its six sites EMBL’s many groups and teams work across the life sciences in interdisciplinary and collaborative ways. Meet and join this community on Bluesky, with EMBL starter pack 🦋 bsky.app/starter-pack/e…

Wonderful news to end the year with: the agreement between the European Union and Switzerland, which includes Switzerland's association with Horizon Europe, has been signed! I look forward to welcoming our colleagues from Switzerland back into the ERC!

EMBO is on Bluesky, and we look forward to meeting you there! bsky.app/profile/embo.o…

Please find EMBO at: bsky.app/profile/embo.o… We look forward to meeting you there!

EMBO shares news and updates on the alternative platform now. We'd love to stay connected! Find us there:

You can find EMBO at the other platform for short posts now. Become part of the #lifesciences community there, and follow us for the latest news and updates!

“The authors then showed that scanning ultrasound activated resident microglial cells that took up Aβ into their lysosomes.”

Interesting: nature.com/articles/d4158… - low quality papers linking some seemingly random phenotypes eg in UKBiobank, "flooding" the literature. Exploring all possible combinatorial possibilities of phenotype combinations sounds like a science business model now...

Hierarchical Reasoning Model This is one of the most interesting ideas on reasoning I've read in the past couple of months. It uses a recurrent architecture for impressive hierarchical reasoning. Here are my notes: