Jim Hughes (@tjh43) 's Twitter Profile
Jim Hughes

@tjh43

Life Raft Group. Daughter Nancy (1967-2005) SDH-deficient GIST. Veteran. Telecom career. Community advocate. Literacy matters. @tjh43.bsky.social

ID: 23725057

calendar_today11-03-2009 04:57:31

331 Tweet

103 Followers

233 Following

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Targetable Receptor Tyrosine Kinase in Metastatic Pheochromocytoma and Paraganglioma: A Future Journey for Anlotinib? | Journal of the Endocrine Society | Oxford Academic academic.oup.com/jes/article/8/…

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Prevalence and prognosis of hypoxia‐inducible factor‐2α (HIF‐2α) pathway gene mutations across advanced solid tumors - CAM4-13-e7358.pdf ncbi.nlm.nih.gov/pmc/articles/P…

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A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors | Clinical Cancer Research | American Association for Cancer Research aacrjournals.org/clincancerres/…

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Adjuvant imatinib in high‐risk resected gastrointestinal stromal tumors: Merely delaying the inevitable? - Sutton - Journal of Surgical Oncology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/js…

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Pre-clinical phaeochromocytoma and paraganglioma models: Cell lines, animal models, and a human primary culture model - ScienceDirect sciencedirect.com/science/articl… A map of pathogenic variants and currently available cell lines and primary cultures ... Figure 1

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Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles - nihpp-rs4410500v1.pdf ncbi.nlm.nih.gov/pmc/articles/P…

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Discontinuation versus continuation of imatinib in patients with advanced gastrointestinal stromal tumours (BFR14): exploratory long-term follow-up of an open-label, multicentre, randomised, phase 3 trial - The Lancet Oncology thelancet.com/journals/lanon…

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Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation: Molecular Cell cell.com/molecular-cell…

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Kura Oncology Announces FDA Clearance of IND Application for Menin Inhibitor Ziftomenib in Advanced Gastrointestinal Stromal Tumors (GIST) | Kura Oncology, Inc. ir.kuraoncology.com/news-releases/…(GLOBEhttps://www.atlassian.com/software/confluence/comparison/confluence-vs-notion

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Clinical characteristics of gastrointestinal stromal tumors with hypoglycemia spandidos-publications.com/10.3892/ol.202…

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Autocrine IGF-II-Associated Cancers: From a Rare Paraneoplastic Event to a Hallmark in Malignancy mdpi.com/2227-9059/12/1…

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Cracking the code of DNA circles in cancer, Stanford Medicine-led team uncovers potential therapy | News Center | Stanford Medicine med.stanford.edu/news/all-news/…

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A Review of Genomic Testing and SDH‐ Deficiency in Gastrointestinal Stromal Tumors: Getting to the GIST - Florou - 2025 - Cancer Medicine - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/ca…

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Recent Advances in Succinate Dehydrogenase Deficient Gastrointestinal Stromal Tumor Systemic Therapies | Current Treatment Options in Oncology link.springer.com/article/10.100…

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Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles | Nature Communications nature.com/articles/s4146…

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Genome‐Wide DNA Methylation and Copy Number Alterations in Gastrointestinal Stromal Tumors - Kleijn - 2025 - Genes, Chromosomes and Cancer - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/gc…

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Single Nuclei-Derived Molecular Subtypes of Gastrointestinal Stromal Tumors Correlate with Clinicopathologic Features and Predict Clinical Outcomes | bioRxiv biorxiv.org/content/10.110…

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Characterization of hereditary tumor risk in individuals with SDHA germline variants. | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…