Super proud of the vascular atlas team Sam Barnett Ana-Maria Cujba Teichlab Lu(Ling) Yang Anna Randi Lab Noseda_lab NHLI Imperial College London Imperial Medicine What an epic achievement and great data demonstrating the diversity of human vascular cells nature.com/articles/s4159…

Latest paper out in nature this week: an atlas integrating 36 single-cell transcriptomic datasets spanning 26 protocols for making neural hashtag#organoids Effort led by Treutlein lab Fabian Theis and Gray Camp In Figure 4 you can also find the pojection of the neural

What an atlas from the @TeichLab and Noseda_lab! 🤯 Sam Barnett (Sam Barnett), @Ana_Cujba, and Ling Yang (Lu "Ling" Yang 👩‍🔬🧬💻) developed a #vascular cell atlas integrating #SingleCell data of 19 organs and tissues. 🔖 Nature Medicine: go.nature.com/3Ou3B8e 💬: bit.ly/4g70Sxm

It was a pleasure to give a talk at the #HCA2024Asia Human Cell Atlas meeting. I really enjoyed catching up with some Wellcome Sanger Institute alumni and had some fascinating discussions with amazing scientists like Drew Neavin #HumanCellAtlas #Neuroscience #SingleCell #Bioinformatics

Today we’re sharing an initial set of cell models that bring together #SingleCell & imaging data in a centralized place. They come with a suite of resources so they’re easy to run + further develop to quickly uncover the mechanics of how cells work czi.co/4g1jTSa

Really fun to write this paper on spatial transcriptomics with Sarah Buddenborg, PhD . It’s an exciting technique that has a lot of potential in Parasitology for new insights.

Are you keen to work with an exciting team? We are advertising a postdoc position jobs.ac.uk/job/DLW091/res… Looking forward to see great applicants! NHLI Imperial College London

Absolutely amazing!

Very excited to see this work out at Nature Methods Our lab's RNA velocity toolkit cell2fate ✅all the boxes if you're 1⃣looking for complex & weak dynamical signals 2⃣driver gene programmes 3⃣Cell fates in Spatial Transcriptomics! See the "X"torial shared below: #bioinformatics

Interested in exploring Vevo Therapeutics’s massive Tahoe-100M single-cell perturbation dataset? #Scanpy now supports out-of-core analysis, powered by Dask—allowing you to seamlessly work with a single huge AnnData object without loading everything into memory. 🔗 theislab.github.io/vevo_Tahoe_100…

Thrilled to share our new Nature Communications study w/ Sam from Noseda_lab on early vs late #COVID19 lung damage 🫁. Using single-cell & histopathology-informed #SpatialTranscriptomics, we uncovered key biomarkers & immune patterns. Thanks to collaborators & UK-CIC Human Cell Atlas

Amazing news for Human Cell Atlas

How can causal machine learning help answer causal questions in single-cell genomics—like how genes interact and influence phenotypes? Our latest Nature Genetics paper explores this challenge, along with approaches to generalizability, interpretability, and modeling cell dynamics.

Ever wondered what a snapshot of single cell/spatial dataset can reveal? scCellFie - a scalable tool that goes beyond gene expression, making metabolic analysis possible 3-2-1 Say GENES🤳 BioRxiv doi.org/10.1101/2025.0… TRY NOW sccellfie.readthedocs.io #DataScience #Bioinformatics

Amazing work by the GBM-SPACE team atlassing one of the deadliest cancers #glioblastoma at multimodality, & coupled the elegant scDORI framework. Revealing a high-res spatiotemporal cell trajectory from tumour heterogeneity & plasticity at both cellular and molecular levels #GBM

Very cool study that discovers novel recessive signals in a Exome sequencing of British South Asians population! 🧬 #Bioinformatics #exome #exomesequencing #populationgenetics #Genetics #datascience

Alzheimer’s disease 🧠starts with a molecular domino effect - but what triggers the first piece to fall? In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇 science.org/doi/10.1126/sc…

🚨 We’re hiring Wellcome Sanger Institute! Join us as a Postdoc or ML Scientist to build generative & foundation models for biology. 🧬 Spatial + single-cell omics 🧠 Diffusion, transformers, multimodal data 💊 Drug discovery via Open Targets Apply: Postdocs in computational biology

📢 Omer Ali Bayraktar Mo Lotfollahi & colabs at Wellcome Sanger Institute are assembling the Open Targets funded Neuroimmune Team 🧠🧬 Leverage AI to uncover neurodegeneration Tech Spec: sanger.wd103.myworkdayjobs.com/en-US/Wellcome… Postdoc AI: sanger.wd103.myworkdayjobs.com/en-US/Wellcome… #SpatialTranscriptomics #Neurodegeneration