
Tetsuhiro Harimoto
@tetsuharimoto
NIH NCI F99/K00 postdoctoral fellow @harvard @wyssinstitute #mooneylab | PhD @columbia @tdanino lab | MIT TR35, Honjo foundation fellow, @UofT alum
ID: 954071132902223872
18-01-2018 19:20:58
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Our latest paper engineering bacterial swarm patterns as biosensor readouts is out in Nature Chemical Biology! Led by @anjalidoshi16, Marian Shaw, collaborating w/ Andrew Laine, Jia Guo, we encode inputs like copper in visible patterns & decode w/ AI. Congrats all! nature.com/articles/s4158…



New preprint! Engineered bacteria launch and control an oncolytic virus biorxiv.org/content/10.110… Exciting work from Zak Singer jpabon & lab engineering bacteria to deliver viral RNAs that launch viral spread. We also engineer the virus to depend on bacteria. Congrats all!


Looking forward to visiting Cornell BME next week! events.cornell.edu/event/bme_spec…

Excited to share our new preprint! We program probiotic bacteria to create a next generation anti-tumor vaccine that stimulates tumor neoantigen-specific immunity to control and eradicate solid tumors Columbia CMBS Columbia BME. biorxiv.org/content/10.110…


Bacteria-based living drugs can treat a broad range of diseases. In this Review, the Danino lab discuss the translational challenges of engineered bacterial therapeutics and how synthetic biology and nanomedicine can help overcome them. Columbia University go.nature.com/3rM7z4m


New paper today! Rosa, @cgurbatri and team engineer probiotics that make synthetic antigens to “paint” cancer cells and direct CAR-T cell activity. Enables targeting cells lacking TAAs. Bacterially produced chemokines also help CAR-Ts. w/Arpaia Lab doi.org/10.1126/scienc…







New paper in collaboration w/The Arpaia Lab out in Nature today! Andrew Redenti, Jongwon Im and team engineer E. coli Nissle probiotic as cancer vaccines nature.com/articles/s4158… Columbia BME Herbert Irving Comprehensive Cancer Center. Congrats all!!

Congrats Fangda Li and team! Another great collab w/ Tal Danino's lab out today in Science Immunology! Programmable bacteria synergize with PD-1 blockade to overcome cancer cell–intrinsic immune resistance mechanisms. Microbiology & Immunology at Columbia University Columbia CMBS Herbert Irving Comprehensive Cancer Center science.org/doi/10.1126/sc…

Our review on living medicine delivery is now out in NatRevMaterials, written in collaboration with Wei-Hung Jung! We outline how synthetic biology and materials science can synergize to develop a new generation of living therapeutics nature.com/articles/s4157…