Taro Yamanaka (@taroy_oncology) 's Twitter Profile
Taro Yamanaka

@taroy_oncology

Medical oncologist 🇯🇵 | National Cancer Center Hospital, Japan | Breast, GYN, rare & GU cancers | All views my own.

ID: 1711865261299531776

calendar_today10-10-2023 22:04:23

176 Tweet

107 Takipçi

396 Takip Edilen

Dr.Monica Avila (@mavilamd) 's Twitter Profile Photo

No surprise FDA Oncology approval expedited to 03/26 as #Rosella trial #SGOAM26 confirms OS benefit with 45% reduction in hazard with nearly double number of patients alive at 18mo mark (27 vs 46%) 🎊 in combo arm of Relacorilant and nab-tax SGO

No surprise <a href="/FDAOncology/">FDA Oncology</a> approval expedited to 03/26 as #Rosella trial #SGOAM26 confirms OS benefit with 45% reduction in hazard with nearly double number of patients alive at 18mo mark (27 vs 46%) 🎊 in combo arm of Relacorilant and nab-tax <a href="/SGO_org/">SGO</a>
Dr.Monica Avila (@mavilamd) 's Twitter Profile Photo

RAMP201 impacts low grade #ovariancancer even in KRAS wild type. Impressive 12.6mo DOR for KRASm with over 50% of pts still on therapy at 1yr. But wait...the wild types benefit with 7mo DOR and 30% on therapy >1yr. Let's confirm it in #RAMP301

RAMP201 impacts low grade #ovariancancer even in KRAS wild type. Impressive 12.6mo DOR for KRASm with over 50% of pts still on therapy at 1yr. But wait...the wild types benefit with 7mo DOR and 30% on therapy &gt;1yr. Let's confirm it in #RAMP301
Dr.Monica Avila (@mavilamd) 's Twitter Profile Photo

First came Abemaciclib/Fulvestrant by Green et Al in ER positive endometrioid cancers but wait...PFS is promising for cousin Abemaciclib/Letrozole in ph II #GOG3039 at #SGOAM26 with 6mo PFS 56.9% and median of 9.5mo with >50% pts still on at over a year. The GOG Foundation Inc. SGO

First came Abemaciclib/Fulvestrant by Green et Al in ER positive endometrioid cancers but wait...PFS is promising  for cousin Abemaciclib/Letrozole in ph II #GOG3039 at #SGOAM26 with 6mo PFS 56.9% and median of 9.5mo with &gt;50% pts still on at over a year. <a href="/GOG/">The GOG Foundation Inc.</a> <a href="/SGO_org/">SGO</a>
Moffitt Cancer Center (@moffittnews) 's Twitter Profile Photo

Live from #SGOAM26 Plenary Session: Marilyn Huang, MD (UVA Comprehensive Cancer Center) presents a Phase II trial of abemaciclib plus letrozole in recurrent or persistent endometrioid endometrial carcinoma. Key takeaways: • Abemaciclib plus letrozole demonstrated clinically meaningful

Live from #SGOAM26 Plenary Session: Marilyn Huang, MD (<a href="/UVACancerCenter/">UVA Comprehensive Cancer Center</a>) presents a Phase II trial of abemaciclib plus letrozole in recurrent or persistent endometrioid endometrial carcinoma. 

Key takeaways:
• Abemaciclib plus letrozole demonstrated clinically meaningful
Giuseppe Caruso (@gcarusomd) 's Twitter Profile Photo

April 10, 2026 Big day in #gynonc. Two pivotal studies (KEYNOTE-B96 and ROSELLA) on platinum-resistant recurrent ovarian cancer were published simultaneously in The Lancet—poised to reshape clinical practice. For a space that has long needed breakthroughs, this feels like a

Taro Yamanaka (@taroy_oncology) 's Twitter Profile Photo

Trastuzumab pamirtecan (DB-1303/BNT323) shows encouraging activity in previously treated, HER2-expressing advanced/metastatic endometrial cancer at #SGOAM26. ✅ Confirmed ORR: 49.3% ✅ Responses seen across HER2 expression levels ✅ Manageable safety profile SGO #gyncancer

Trastuzumab pamirtecan (DB-1303/BNT323) shows encouraging activity in previously treated, HER2-expressing advanced/metastatic endometrial cancer at #SGOAM26.
✅ Confirmed ORR: 49.3%
✅ Responses seen across HER2 expression levels
✅ Manageable safety profile
 <a href="/SGO_org/">SGO</a> #gyncancer
Taro Yamanaka (@taroy_oncology) 's Twitter Profile Photo

SISTER study at #SGOAM26. ✅ First national randomized trial of social support in Black women with high-risk EC ✅ 1:1 peer support improved treatment completion ✅ Supportive care trials in this population are feasible An important report for EC care. SGO #gyncancer

SISTER study at #SGOAM26.

✅ First national randomized trial of social support in Black women with high-risk EC  
✅ 1:1 peer support improved treatment completion  
✅ Supportive care trials in this population are feasible  

An important report for EC care.
<a href="/SGO_org/">SGO</a> #gyncancer
Taro Yamanaka (@taroy_oncology) 's Twitter Profile Photo

#NRG-GY033 at #SGOAM26: Exemestane + darolutamide + leuprolide acetate in recurrent adult-type ovarian granulosa cell tumor ✅ ORR 6.25%, below the prespecified threshold ✅ Stable disease in 62.5% pts Negative trial. How can hormonal therapy in AGCT be further advanced? SGO

#NRG-GY033 at #SGOAM26: Exemestane + darolutamide + leuprolide acetate in recurrent adult-type ovarian granulosa cell tumor
✅ ORR 6.25%, below the prespecified threshold
✅ Stable disease in 62.5% pts
Negative trial. How can hormonal therapy in AGCT be further advanced? <a href="/SGO_org/">SGO</a>
Yukihide Ota (@yukihideota) 's Twitter Profile Photo

I am honored to have received the Best Basic Science Award at the SGO 2025 Annual Meeting. I am truly grateful for this recognition and will continue advancing research in gynecologic oncology to make a meaningful difference for patients. SGO #CRepHS #WashU

Taro Yamanaka (@taroy_oncology) 's Twitter Profile Photo

Updated Ph1 data for Sofe-M (LY4170156) in recurrent PROC at #SGOAM26. ✅ ORR 50% in a heavily pretreated cohort ✅ Activity across FRα expression levels, including prior MIRV exposure ✅ Favorable safety, with low neuropathy and no keratopathy Ph3 ongoing! SGO @gyncancer

Updated Ph1 data for Sofe-M (LY4170156) in recurrent PROC at #SGOAM26.

✅ ORR 50% in a heavily pretreated cohort
✅ Activity across FRα expression levels, including prior MIRV exposure
✅ Favorable safety, with low neuropathy and no keratopathy

Ph3 ongoing!
 <a href="/SGO_org/">SGO</a> @gyncancer
Moffitt Cancer Center (@moffittnews) 's Twitter Profile Photo

Emerging data at the #SGOAM26 Plenary: Toon Van Gorp, MD, PhD (UZ Leuven) shares results on combining carboplatin and pembrolizumab with or without bevacizumab in first-line recurrent or metastatic cervical cancer. Key takeaways:
• Robust antitumor activity with ORR ~66%,

Emerging data at the #SGOAM26 Plenary: Toon Van Gorp, MD, PhD (<a href="/UZLeuven/">UZ Leuven</a>) shares results on combining carboplatin and pembrolizumab with or without bevacizumab in first-line recurrent or metastatic cervical cancer.

Key takeaways:
• Robust antitumor activity with ORR ~66%,
JAMA (@jama_current) 's Twitter Profile Photo

Uterine cancer is the fourth most common cancer in women in the US, with an estimated 68 270 new cases and 14 450 cancer deaths projected to occur in 2026. 📄 This Review summarizes the epidemiology, clinical presentation, and diagnosis of endometrial cancer.

Uterine cancer is the fourth most common cancer in women in the US, with an estimated 68 270 new cases and 14 450 cancer deaths projected to occur in 2026. 

📄 This Review summarizes the epidemiology, clinical presentation, and diagnosis of endometrial cancer.
Zymeworks Inc. (@zymeworksinc) 's Twitter Profile Photo

We are thrilled to be sharing new clinical data from our first-in-human multicenter open-label study of our folate receptor α (FRα)–targeting antibody-drug conjugate (ADC). Abstract CT306, will be held Tuesday, April 21, 2026 at 2:30 – 4:30 pm Pacific Standard Time (PST).

We are thrilled to be sharing new clinical data from our first-in-human multicenter open-label study of our folate receptor α (FRα)–targeting antibody-drug conjugate (ADC).

Abstract CT306, will be held Tuesday, April 21, 2026 at 2:30 – 4:30 pm Pacific Standard Time (PST).