We’ve made enormous progress on cancer. To take just one example: Death rates from leukemia in young children have plummeted by 93% since 1950.

Nature is healing

This week on Construction Physics, an engineering history of the Manhattan Project. construction-physics.com/p/an-engineeri…

Neil Chilson ⤴️⬆️🆙📈 🚀 I concur directionally with this in some ways but I think the point these folks are making is that a plant cannot eg design novel bacteria or solve open questions in mathematics, and a plant is also not infinitely replicable at near zero marginal cost. A system with those

Before LLMs became multimodal I thought that it’d lead to a big leap in capabilities (lots of new, diverse data that’s really different from text, making the sample distribution much larger, so increasing generalization a ton). But then I was disappointed when this didn’t really

Making multimodal LLMs was both much easier than I expected and much lower impact than I expected

Twitter hive mind, I need your help! What mechanistic biological/chemical/physical insights have resulted from analyzing AI models trained on scientific data?

Amazing: The number of Airplanes the US produced during WWII is greater than all commercial airplanes produced in the *entire history of aviation.* Could America do this again today?

This morning, Foundation for American Innovation 🇺🇸🚀 published ten essays from leading legal scholars and practitioners as part of a symposium we hosted in early September. The After Fair Use Collection address the legal challenges for copyright law in handling transformative technologies.

What will AI look like by 2030 if current trends hold? Our new report zooms in on two things: (1) whether scaling continues (compute, data, power, capital), and (2) the capabilities this enables—especially for scientific R&D.

New SOTA on ARC-AGI - V1: 79.6%, $8.42/task - V2: 29.4%, $30.40/task Custom submissions by Jeremy Berman and Eric Pang are now the best known solutions to ARC-AGI Both: * Are open source * Use Grok 4 * Implement program-synthesis outer loops with test-time adaptation

New from Arc Institute: the first functional AI-generated genomes. This is a conceptual breakthrough, but it may also unlock new strategies for combating antibiotic resistance.

The FAI energy team is (once again) hiring! Seeking a project manager to serve as the operational engine of FAI’s efforts on permitting reform, capital stack innovation, and competitiveness. Please share widely! Link below.

This is an amazing and awe-inspiring moment! It also raises concerns, naturally. Now would be a great time for the federal government to release a new policy framework for the firms that produce synthetic nucleic acids! 🤞

We're cohosting a book launch party in DC on September 26th with Stripe Press for Brian Potter's new book 🥳 Register here: luma.com/rtonxk5h?tk=pI…