🧬Inborn Error of Immunity⚠️
➡️ 'VEXAS' Syndrome
▪️ one of the newest autoinflammatory disorders
🗓️ first identified in 2020
- number of known patients growing rapidly
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sciencedirect.com/science/articl… #bioinformatics #openscience #rstats #itrtg #raredisease #immunology
Yogesh Yogesh Kulathu gave a great talk on branched ubiquitin chains introduced by John Christianson Lab at the Oxford Ubiquitin Club. It seems the p97 system is again the main player in the story 😊.
New research reveals the hidden role of ubiquitin protein in shaping fear memories, potentially driving PTSD in females. This opens up new avenues for gender-specific therapeutic treatments.
#neuroscience
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Rabbi Mordechai Lightstone Mike Cohen ([email protected]) Chabad.org A being able to add a cubit to the measure of physical being must out of necessity have full paternal DNA everyone else lacks due to emnity between the sperm & egg via ubiquitin. As such, for being the only begotten of the father full of grace & truth, the almighty is FULLY MALE.
🔎Our recent findings published in J Cell Science reveal the involvement of two ubiquitin conjugating enzymes- UBE2D1 and UBE2D2 in VEGFR2 proteolysis and turnover, that regulate angiogenesis.
✅Link to full article: journals.biologists.com/jcs/article/do…
#angiogenesis #rtk #ubiquitination
🔉If you miss our paper about #autophagy and ESCRT on endolysosomal repair in #dicty just check out the final version finally online eLife - the journal
elifesciences.org/articles/85727…
Find now all information and supplementary material !
🚨 New release from our group !
If you want to know more about an E3-ligase regulating the crossroads of ESCRT and autophagy pathways just check out our paper out in eLife - the journal 👇👇
elifesciences.org/articles/85727
💍TRAF trimers form #ImmuneSignalling networks via RING domain dimerization
🖊Catherine Day & team University of Otago
➡bit.ly/41KtfcX
#Immunology #TumorImmunology #ubiquitin