The authors believe that acute SARS-CoV-2 infections could have caused long-lasting structural modifications to the skeletal muscle microvasculature, which could explain the fatigue post-exertion.

H/t ⁦Kate Pritchard⁩ news-medical.net/news/20230220/…

“Results showed that skeletal muscle samples from #LongCovid patients had fewer capillaries, compared to [controls].. authors believe.. long-lasting structural modifications to the skeletal muscle microvasculature.. could explain post exertional malaise.”news-medical.net/news/20230220/…

Cerebral microvasculature structure, function and dysfunction after ischaemia.

Source: nature

#neuroscience #MedTwitter

Confirmation of my early work. I saw this two years ago.

December 1, 2021
SARS-CoV-2 IS PRIMARILY A DISEASE OF THE SPIKE PROTEIN’S INTERACTION WITH THE MICROVASCULATURE

wmcresearch.org/the-spike-prot…

Today's ESD. Fascinating microvasculature here. I am sure most of you here at #GITwitter know what the pathology is.
Anyway, thought it is interesting enough to share

Anatomy of Hepatic Microvasculature

▪️Normal vs Cirrhosis
▪️Note: 3 major changes
1️⃣ Defenestration
2️⃣ Constriction of sinusoids
3️⃣ Activation of stellate cells
▪️Microvascular is key to portal HTN
▪️Important in understanding ascites

#LiverTwitter 👊

Post-COVID nerve fiber pathology within the human eye

(other reports found microvasculature abnormalities as well)

bjo.bmj.com/content/106/12…

This study using an MRI and inhaled xenon gas found anomalies in oxygen exchange in the alveolar sacs of the lungs and ’abnormal trimming‘ in the microvasculature that delivers oxygenated blood to the lungs.

news.westernu.ca/2022/06/innova…

Daily Kos: 'Canadian Health Service Finds Repeated Covid Infections Damages Blood System, Causes Long Covid'

'Repeated COVID-19 infections compound the damage to the microvasculature, increasing the likelihood of long-COVID symptoms..'

dailykos.com/stories/2023/1…

Excited to share the in vivo validation of our VASCOVID device! Let’s advance microvasculature health monitoring in the intensive care. Join Marta today at 6:00 PM. Turgut Durduran ICFO UCI Parc Taulí #vascovidEU #OpticaBiophotonics24

Just in time for the holidays!
Thrilled to share our latest work at KammLab. We developed a novel microfluidic approach to study human lymphatic microvasculature!
doi.org/10.1002/advs.2…

Massachusetts Institute of Technology (MIT) Massachusetts Institute of Technology (MIT)MechE

IMPORTANT:
❗New evidence that the #SARSCoV2 S-protein
➡️may have a direct pathogenic action on cardiac pericytes with subsequent damaging of the heart’s microvasculature, through pericyte detachment, death, and decreased vascular coverage, thus disrupting the coronary…

#GiTwitter , understanding the basic adenoma is 🔑 before assessing complex polyps. 💡BLI/NBI highlights microsurface/microvasculature, NOT the pit. For precise pit-pattern exam, indigo/crystal violet is needed (exception: type II-O pit in SSLs seen well w/ BLI/acetic acid)

Our latest release on placental microvasculature..Just in time for the holidays! ⁦HaaseLab⁩ science.org/doi/10.1126/sc…

Please check out our new protocol for differentiating human #iPSC derived #cardiacpericytes published Circulation. These cells are integral for coronary microvasculature. Congrats Simon Shen Chun Shane Zhao and Stanford CVI @Illumina scientists

cvi.stanford.edu/mission/news_c…

Use your buttons 🔘‼️ NBI markedly improves visualization of cancerous tissues characterized by abnormal surface and vascular patterns

If with magnification 👉 more accurate assessment of mucosal microstructure and microvasculature 🏆💯 #GITwitter misjournal.net/article/view/5…

🔔Postdoc opportunity🔔
We have a position open to develop and apply ultrasound imaging to study remodeling of the islet microvasculature in T1D and to develop imaging diagnostics. Feel free to email me - see benningerlab.com.
Apply here: cu.taleo.net/careersection/…

“Endothelial dysfunction is a hallmark mechanism in Long Covid with impairment of the microvasculature correlating with persistent symptoms” link.springer.com/article/10.100…

Skeletal muscle biopsies:
➡️'SarsCoV2 may have caused immune-mediated structural changes of the microvasculature explaining the exercise-dependent fatigue and muscle pain'
➡️Clear signatures in skeletal muscles with macrophage infiltration
➡️ #LongCovid
medrxiv.org/content/10.110…

Congratulations to BCaseMD, Itsik Ben Dor Ron Waksman Hayder Hashim et al. on their recent publication in American Journal of Cardiology!

Understanding Patient Characteristics and Coronary Microvasculature: Early Insights from the #CMD Registry

sciencedirect.com/science/articl…