My warmest congratulations to Jiashu Chu on his PhD defense! It's been a pleasure to supervise you and explore immune signaling in #Marchantia together University of Zurich!
All the best for the future ⭐️
And congrats to the other Doktoreltern Cyril Zipfel and Tom DeFalco!

HOLY SHIT. These mechanistic findings about covid's impact on immune signaling seem potentially HUGE!

Let's dig in...

(And I'm honestly ecstatic right now, because this paper seems to support my hypothesis about *how* I personally avoided LC.)

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Metabolic disorders are driven by dysfunctional immune signaling in #MASLD .
sciencedirect.com/science/articl…

#Mitochondria driven innate #immune signaling and #inflammation in #cancer growth, immune evasion, and therapeutic resistance
sciencedirect.com/science/articl…

Just learned that the glyco-cyclic ADPR immune signaling molecules we discovered,  2’ cADPR and 3’ cADPR, are available as purified products at Biolog: biolog.de/news#news20230…

Very useful for researchers studying immune signaling in bacteria and plants

Congrats to Dr. Gita Abhiraman in successfully defending her thesis today on 'Modulating immune signaling with engineered cytokines.' 👏🎉 Great work!

A new class of immune signaling molecules generated by TIR domains: histidine conjugated to ADP-ribose

Check out our preprint: tinyurl.com/hisADP

A fantastic collaboration with the Tamulaitiene and Kranzusch labs

A 🧵 1/9

Review of #sepsis -induced coagulopathy (SIC) analyzes complex pathophysiology w/ focus on role of procoagulant immune signaling in hemostatic activation: tissue factor production, thrombin generation, endotheliopathy, & impaired antithrombotic functions.

buff.ly/495fWrg

Trey Westbrook presenting antiviral innate and adaptive immune signaling in #TNBC in the context of STT sensitivity #AACR2023

We present current knowledge on the functional aspects of #mitophagy and its crosstalk with innate #immune signaling during #infection

👇
sciencedirect.com/science/articl…

On the program at Vascular Biology 2023:

Alejandro Adam, Associate Professor at Albany Medical College, will present

'Endothelial control of innate immune signaling during shock'

Lab: adamlabs.org

Registration at navbo.org/vb2023

#NAVBO2023 Alejandro Adam

I’m very happy to present my poster at #2023ISMPMI on Monday in the Plant Immunity Mechanisms session II (12:30 to 13:15). Come by P-286 if you want to chat about EDS1-PAD4 immune signaling and are interested in what a cysteine protease potentially has to do with it 🌱

SARS-CoV-2 persistence can cause Long Covid.

Long Covid can be diagnosed using two biomarkers of chronic viral infection.
- FYN (immune-signaling marker of ongoing infection)
- SARS-CoV-2 antisense RNA (viral reproduction intermediate)
medrxiv.org/content/10.110…

Want to study the DNA damage response in yeast and mice and in vitro? We also use mammary organizes. Studying links to innate immune signaling and tumor suppression. We have a postdoc slot! Please DM or email ski.edu/petrini

Excited to share our recent study in Cell led by Giuseppe Leuzzi on the dual role of the DNA translocase SMARCAL1 in regulating innate immune signaling and the expression of the PD-L1 immune checkpoint factor! authors.elsevier.com/a/1iWe5L7PXqPXc

Modulating the #innate #immune system in #cancer has being disappointing. This review presents a framework where distinct innate immune signaling pathways activate 5 key dendritic cell activities that are important for T cell-mediated immunity. Most approaches in the clinic have

Immune signaling induced by plant Toll/interleukin-1 receptor (TIR) domains is thermostable

A new immune signaling molecule, S-adenosyl methionine conjugated to AMP. Incredible!

Innate immune signaling in MDS.

🤯presentation🤯 by Dominik Wolf.

Go read up about
NLRP3
Myddosome
pyroptosis

Brilliant work #EHA2023 #mdssm European Hematology Association

Researchers discovered higher than usual levels of the immune signaling molecule interleukin-1B (green) in neurons (outlined in red) from the brains of alcohol-dependent mice.

Credit: Scripps Research

#MedTwitter