It was definitely worth taking a short break from parental leave to present at the epic #EMBOphagocytosis workshop! Big thanks to the organizers and EMBO for the childcare grant and to Che Stafford and Matthias Mann Lab for the support #proteomics #efferocytosis

Did I just pass my qualifying exam? Yes absolutely. Did I display a poem that chatgpt wrote about efferocytosis to my committee at the end of my PowerPoint? Oh absolutely I did. 😂😂

My postdoc work in the Perry Lab MSKCC Memorial Sloan Kettering Cancer Center is live! We found an interesting link between the microbiota and regulation of efferocytosis, and how this can contribute to susceptibility to inflammation. Tweetorial below. biorxiv.org/content/10.110…

Huge congratulations to Sho Morioka, other lab members, and collaborators on a new way to boost efferocytosis and dampen inflammation in disease models authors.elsevier.com/a/1gIGbL7PXiqv5

🚨JOB ALERT MACROPHAGE BIOLOGY

4yr MRC-funded post-doc

Are you interested in how phagocytes recognise and respond to tissue damage?

Want to know how efferocytosis effects the fate and function of macrophages?

If so, we have the job for you.

jobs.ac.uk/job/COY771/pos…

Further reading for #Autophagy #eSymposia

#Review by Doug Green on The clearance of dead cells by efferocytosis!

Access here: go.nature.com/2VjQtb7

#efferocytosis
#celldeath

FREE pdf: rdcu.be/b78HT

Scientists untangle how a compound found in many fruits and vegetables supports macrophages’ ability to clear out debris and apoptotic cells—a finding that may inform interventions for conditions involving impaired #efferocytosis . @SciSignal scim.ag/2Sg

We performed a genome-wide pooled CRISPR knockout screen in primary mouse macrophages for efferocytosis regulators and identified Wdfy3 as a novel one required for both the uptake and degradation of apoptotic cell cargo. nature.com/articles/s4146… Nature Communications

🚨 #postdoc opportunity InflammationResearch

Medical Research Council-funded #postdoc position to understand the effects of efferocytosis on #macrophage fate and function. Full details 👇

elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…

British Society for Immunology Society for Mucosal Immunology

14/14 - SUMMARY

☞The initial infiltrate in pneumonia contains neutrophils and bacteria
☞The later infiltrate - seen up to weeks after clinical stability - is largely made up of macrophages engaging in efferocytosis, cleaning up apoptotic debris

The Perry Lab Memorial Sloan Kettering Cancer Center is excited to share another story from the lab, led by postdoc Pedro Pedro Saavedra 'A microbiota-derived metabolite instructs peripheral efferocytosis'. A breakdown of what we found and its broader relevance follow below. biorxiv.org/content/10.110…

Integration of cell death signals | #CellDeath #Efferocytosis | Sourav Ghosh Yale School of Medicine Yale Neurology | Review Nature Rev Immunol rdcu.be/caKOV

You are what you eat and how you digest it! This is not only the case for us, but also our macrophages. Have a quick read on open questions in the field of #efferocytosis ! frontiersin.org/articles/10.33…

New paper published - Charles Yin, MD PhD and I review the regulation of immune cell responses to efferocytosis, and the role of efferocytosis in our defence against pathogens. #macrophages #efferocytosis
frontiersin.org/articles/10.33…

Scientists untangle how a compound found in many fruits and vegetables supports macrophages’ ability to clear out debris and apoptotic cells—a finding that may inform interventions for conditions involving impaired #efferocytosis . @SciSignal scim.ag/2PC

Another New Year Gift - this time with Petri Kovanen and #AmirhosseinSahebkar ! In our new review we explore the role of the # #molecular #pathways related to the #caspase dependent #events in #efferocytosis in the context of #atherosclerosis . International Lipid Expert Panel (ILEP)
sciencedirect.com/science/articl…

Outstanding work by medical student and HHMI NEWS fellow Alyssa M. Flores, MD on a novel “macrophage selective Trojan horse molecule that activates efferocytosis. Alyssa is going to be a powerhouse physician scientist. #VascularDiscovery19 @vasc_med

Check out our exciting new work highlighting how macrophage efferocytosis and the metabolism of apoptotic cell-derived nucleotides induces Myc dependent proliferation and the expansion of pro-resolving macrophages to repair tissue injury!

cell.com/cell-metabolis…

Congratulations to Sophia Maschalidi and coauthors on a lovely journey discovering a key role Slc7a11 as a natural brake for efferocytosis by dermal DCs and the relevance to diabetic skin wound healing! rdcu.be/cOjKE

So thrilled to receive a NIGMS R35 award which will support our studies on endocytic membrane trafficking and efferocytosis in macrophages! We are hiring! Anyone interested in Cell Biology, please contact me!

JOB ALERT Edinburgh UK

We're looking for a post-doc to study how efferocytosis regulates macrophage fate and function during disease. 4yr MRC-funded, with @chris_d_lucas Calum Bain Will Wood and Adriano Rossi InflammationResearch

Please spread the word

elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…