#EverydayBST
Elbow mass
Diagnosis?
See answer 👇
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

#EverydayBST
Spinal tumor?
See answer👇
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

USCAP 2024 with some of our fabulous Residents and Attendings. #USCAP2024 #baltimore #pathology

#EverydayBST
Early signs of osteoarthritis
1⃣Loss of blue color of chondrocytes, the sections look more pink
2⃣Chondrocyte clustering
2⃣Duplication of tide mark
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

#EverydayBST
Young patient with a multicystic lesion of the pelvis with fluid levels.
Radiologic diagnosis: Aneurysmal bone cyst
But then they sampled the fluid and...👇
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

#EverydayBST
Hyaline cartilage-producing neoplasm with complete entrapment of preexisting bone trabeculae
Diagnosis? See next 👇
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

✅Denosumab treated giant cell tumor of bone.
Denosumab inhibits the formation of osteoclasts (giant cells) and the neoplastic cells (mononuclear ones) that have an osteoblastic phenotype start forming bone in this peculiar fibrillar pattern
Dr. Nielsen #USCAP2024 #BSTPath …

A closer look at this #USCAP2024 study, evaluating Ibex’s #AI platform's performance in detecting microinvasive breast carcinoma & showing very high accuracy for AI in identifying these minute tumors: eu1.hubs.ly/H08CTzy0 #breastcancer #pathology Brigham and Women's Hospital Stuart Schnitt

We were thrilled to have Zubair Baloch be presented with PAPS Distinguished Service Award 2024
at #USCAP2024 for his undeniable services to Pathology. Dr. Baloch is a true asset to field.

#PAKPATH

#EverydayBST
Degenerative joint disease-histologic findings
Dr. Nielsen-A day in the sign out #USCAP2024 #BSTPath #Pathresidents #PathTwitter #PathX

#EverydayBST
Resection of the proximal radius
Can you figure out the history?
See answer 👇
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

In other areas you can recognize the hyaline cartilage end plate
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

Neovascularization is sign of a prolapsed disc, you can sign it as:
-Fragments of degenerative fibrocartilage (disc) with histologic evidence of prolapse
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

If in appendicular skeleton (long and short tubular bones) call it atypical cartilaginous tumor
If in axial skeleton (flat bones, including the pelvis, scapula, and skull base), call it chondrosarcoma grade 1
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

#EverydayBST
Osteophyte
It is an attempt of the body to repair the articular cartilage
It is fibrocartilaginous and doesn't contain the tide mark
The only cartilage in the body that has a tide mark is the articular cartilage
Dr. Nielsen #USCAP2024 #PathX #PathTwitter

Fracture callus
Left: Bone formation with osteoblastic rimming
Right: Cartilage can look cellular, atypical and with mitosis
Fracture callus can look worrisome on histology and be misinterpreted as a neoplastic process
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX …

#EverydayBST
Myxoid fat tumor differential diagnosis
1⃣2⃣Lipoblastoma
-Young patients, but can be seen in any age group
-Lobulated tumor
-Spindle cell look
3⃣ Myxoid liposarcoma: Cells are round
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

#EverydayBST
Osteopetrosis
-Skeletal sclerosis (increased bone density) caused by osteoclast dysfunction
🔬Mineralized cartilage admixed with trabecular bone
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

🛑There are reports of cases signed as low grade osteosarcoma because the pathologist didn't know that patient had a treated giant cell tumor of bone 🛑
Dr. Nielsen #USCAP2024 #BSTPath #pathology #PathX #PathTwitter

Team CCHMC Pediatric Pathology at #SPP2024 and #USCAP2024 ! See you all in Boston! #CCHMC #pediatricpathology #pedipath #cincykidspathology #wearecincykids #pedipath fellowship