“Could understanding shared mechanisms for multiple long term conditions help us avoid the polypharmacy trap?” asks Miles Witham #UKKW2023 - answers pending…give him a decade!

Did you know that the time from development to clinic for biologics drugs could be significantly shortened by adopting a parallel & integrated approach to drug substance development, drug product manufacturing, & clinical supply?

Cliff Kilgore Steve Taylor As a medical student I was taught about polypharmacy, GPs were blamed. As a GP I was faced with polypharmacy instigated by hospital Drs. It’s still happening eg.statins, BP meds, etc. A pill for every ill. Big Pharma no doubt keen to make more money. Weight loss drugs too!

Polypharmacy: the simultaneous use of multiple drugs by a single patient, for one or more conditions.

#wellness #health #fitness #health ylifestyle #selfcare #motivation #love #health y #beautiful #nutrition #healing

📢 #Rheumatoid arthritis monotherapy in the Jak inhibitors Era. Current prevalence and associated factors in a multicenter study
by Garcia-Salinas R et al

👉 arprheumatology.com/section.php?id…

☑️ Second line of treatments and less polypharmacy were independent factors

Often, polypharmacy is the problem, not the solution.

In the news: FDA Warns People to Avoid Compounded Semaglutide Medicines.

Ask an AI: 'What are compounded Semaglutide medicines?'

How to avoid POLYPHARMACY (taking too many medicines). JAMA overview on DE-prescribing. bit.ly/43BpFmW

Reminded by Lucy Pollock that most older people don't want totake lots of pills & value quality of life over quantity.

So why is there still so much polypharmacy in this group?

Are we doing shared decision making? Is it too hard to forego prevention?

bmj.com/content/364/bm…

This is a must read thread on a very common scenario of how polypharmacy harms patients…

threadreaderapp.com/thread/1667553…

Om Prakash, MD SSRI's can cause weight gain, which can lead to diabetes, which results in being prescribed Metformin as the 1st line of choice. Metformin is rarely effective long-term, it's well-known that most Type 2 diabetics end up on other meds or insulin within 10 - 15 years. Polypharmacy.

1/5 A friend brought his mother to the hospital. She had been diagnosed with Alzheimer's & Parkinson disease. She had signs of both diseases, but this confluence is rare. By looking at the history, I found out that she was taking many drugs & that it all started with #anxiety ...

Polypharmacy: the simultaneous use of multiple drugs by a single patient, for one or more conditions.

#wellness #health #fitness #health ylifestyle #selfcare #motivation #love #health y #beautiful #nutrition #healing

We need your help if you are a health professional caring for older people with frailty and polypharmacy.. Dr Eloise Radcliffe & Dr Kinda Ibrahim are holding workshops online to improve care. Click on this link if you want to help:
tinyurl.com/modifystudy

Jesus Ramirez-Bermudez I see children with #autism among the most abused by #psychiatry . #Polypharmacy is very common.

Updated STOPP/START criteria: version 3, an explicit list of potentially inappropriate medications and potential prescribing omissions in older people with multimorbidity and polypharmacy.

<<New Episode - Advocating for the Patient>>

We are joined by Paul Woodgate - how do we ensure we listen to the patient when designing healthcare? Paul talks about his Diabetes, Parkinson's, and we hear a remarkable tale of the impact of polypharmacy. theauralapothecary.com/58-paul-woodga…

Regional #vaccine production features in the draft pandemic accord, but there is still a long road before this becomes a reality.

Aspen Pharma Prof Peter Hotez MD PhD Presidency | South Africa 🇿🇦 |
🖊️Kerry Cullinan
healthpolicy-watch.news/important-less…

Come on #POTS , please stay stable today and stop spiking to heart rates of 170. I’m sat down for heavens sake and the day has only just began🙈 Anyone else find that #Heat or #stress makes their #pots do things crazier than usual? Any tips to manage? Aside from the polypharmacy

I saw a 95 year man living with dementia last week. He was deteriorating and none of his medications were adding therapeutic benefit and I stopped all 5. This week, he is alert, all his symptoms have resolved and for the first time in months he is reading again #deprescribing 😁

Andy White David Webb Richard Cattell Lancashire and South Cumbria ICB LSC Integrated Care Partnership AuralApothecary Jonathan Underhill Ewan Maule Laura Angus 🏳️‍🌈 🏳️‍⚧️ she/her Vanessa Burgess 🇺🇦 Older people
reducing avoidable admissions - see Pirmohamed paper from last summer. bmjopen.bmj.com/content/12/7/e…
Overprescribing
Safety
Repeat prescribing
Targetting SMRs
If we get all this right ➡️reduce patient harm and burden on patients ➡️reduction in carbon + marine pollution

And so important to better understand common mechanisms of disease, develop common treatments and AVOID POLYPHARMACY! #UKKW2023

Cliff Kilgore Polypharmacy in the elderly is not talked about enough.

The use of multiple medications increases as an individual has more health conditions and as one ages. This has been coined polypharmacy. As an individual takes more medications they are at a greater risk for side effects and drug interactions. RSVP: bit.ly/3C0Ia8p

💊Our latest #Deprescribing #Research feature blog:

#Frail #OlderAdults Taking #Cardio metabolic #Medications : When Less Is More

Read more here: deprescribingresearch.org/frail-older-ad…

#Polypharmacy #Cardio #Heart #Meds