Cardiac Trials(@CardiacTrials) 's Twitter Profile Photo

Just 1 month of DAPT after ACS? This trial showed ticagrelor monotherapy after only 1 month of DAPT to decrease bleeding WITHOUT change in ischemic events. A step in the right direction to decrease risk and pill burden in our patients. ULTIMATE-DAPT Trial, Lancet 2024 ♥️

Just 1 month of DAPT after ACS? This trial showed ticagrelor monotherapy after only 1 month of DAPT to decrease bleeding WITHOUT change in ischemic events. A step in the right direction to decrease risk and pill burden in our patients. ULTIMATE-DAPT Trial, Lancet 2024 ♥️
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The Heart(@ZHeart11768530) 's Twitter Profile Photo

🔴 Trial The Lancet
Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS)

thelancet.com/journals/lance…

🔴  #ULTIMATE_DAPT Trial @TheLancet
Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS)

thelancet.com/journals/lance…
 #cardiotwitter #cardiovascular #MedEd #MedTwitter
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Cardiac Trials(@CardiacTrials) 's Twitter Profile Photo

1/ Just 1 month of DAPT after ACS? This trial showed ticagrelor monotherapy after only 1 month of DAPT to decrease bleeding WITHOUT change in ischemic events. A step in the right direction to decrease risk and pill burden in our patients. ULTIMATE-DAPT Trial, Lancet 2024 ♥️

1/ Just 1 month of DAPT after ACS? This trial showed ticagrelor monotherapy after only 1 month of DAPT to decrease bleeding WITHOUT change in ischemic events. A step in the right direction to decrease risk and pill burden in our patients. ULTIMATE-DAPT Trial, Lancet 2024 ♥️
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Dr Shailesh Singh(@drShaileshSingh) 's Twitter Profile Photo

🚨ULTIMATE-DAPT trial 🏥💊

✅ Ticagrelor alone vs. DAPT (ticagrelor + aspirin) for 12 months post-PCI in ACS patients:

🔍Primary effectiveness endpoint:
Significant reduction in bleeding with ticagrelor monotherapy! 🩹

❌ No increase in adverse ischemic thrombotic events! 🚫…

🚨ULTIMATE-DAPT trial 🏥💊

✅ Ticagrelor alone vs. DAPT (ticagrelor + aspirin) for 12 months post-PCI in ACS patients:

🔍Primary effectiveness endpoint:
Significant reduction in bleeding with ticagrelor monotherapy! 🩹

❌ No increase in adverse ischemic thrombotic events! 🚫…
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Richard Ferraro(@RichardAFerraro) 's Twitter Profile Photo

My quick, ⬆️or ⬇️, top 3 takeaways from with explainations in thread below:

1) Polypharmacy is ⬇️!

What a conference for trimming the meds. B-blockers post-MI took a hit in REDUCE-AMI, while shorter DAPT duration got ⬆️ support from the Ultimate DAPT trial. What's next?

My quick, ⬆️or ⬇️, top 3 takeaways from #ACC24 with explainations in thread below:

1) Polypharmacy is ⬇️!

What a conference for trimming the meds. B-blockers post-MI took a hit in REDUCE-AMI, while shorter DAPT duration got ⬆️ support from the Ultimate DAPT trial. What's next?
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Gregg W. Stone MD(@GreggWStone) 's Twitter Profile Photo

Final poll results: with 277 responses, after ULTIMATE -DAPT, 67% are ready for shorter DAPT regimens after PCI in ACS, with most of those ready for 1 month only. 33% still say 1-year DAPT! Not sure why. No one bleeds until they bleed.

Final poll results: with 277 responses, after ULTIMATE -DAPT, 67% are ready for shorter DAPT regimens after PCI in ACS, with most of those ready for 1 month only. 33% still say 1-year DAPT! Not sure why. No one bleeds until they bleed.
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ダックス医(@DachsClinic) 's Twitter Profile Photo

現在のPCI後のSAPTでクロピドグレルを残す流れというのは、理論上クロピドの方が副作用少ない中で、SMART-CHOICEやSTOPDAPT-2で短期DAPT後のクロピドの有用性が確認され、またある程度長期DAPT後のSAPTもHOST-EXAMでクロピド>アスピリンだったから、という認識で良いのでしょうか?詳しい解説求む。

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Lelly Oboh(@LellyOboh) 's Twitter Profile Photo

JAMA. In old pple, clinicians can consider shorter duration of DAPT post PCI to reduce bleedn risk w/out incr risks of net adv clin events OR major adv CVS events. DAPT x3mths may be optimum. shorturl.at/kHPU6
⚠️

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⚠️固ツイ必読⚠️Drぷーbot@知識ばらまき(@Dr_ppooohh_bot) 's Twitter Profile Photo

✅PCI後のDAPT(2剤抗血小板療法)ってなんで必要なの?目的は?
「サラサラにした方が血管が詰まりにくいから?」

んー少し違います
それなら,もっと多くの人がDAPになってるTかも

キーワードは「ステント血栓症」

mtlnk.net/j_s%253A%252F%…

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Thrombosis & Haemostasis, TH,TH Open(@TH_Journal) 's Twitter Profile Photo

🫀 What is the clinical impact of dyspnoea during DAPT with ? ⤵️

📌 Dyspnoea reported in 20.6% of patients with Ticagrelor
📌 In those switched to ⬇️ dyspnoea at 3/6 months

👉 thieme-connect.de/products/ejour…

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Cardiac Trials(@CardiacTrials) 's Twitter Profile Photo

ULTIMATE-DAPT ~~ Another landmark trial addition to the Cardiac Trials app 📱 of 2024 ♥️

Organized under ACS —> P2Y12 inhibition

apps.apple.com/us/app/cardiac…

ULTIMATE-DAPT ~~ Another landmark trial addition to the Cardiac Trials app 📱 of 2024 ♥️

Organized under ACS —> P2Y12 inhibition

apps.apple.com/us/app/cardiac…
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Cardiac Trials(@CardiacTrials) 's Twitter Profile Photo

~~ Ultimate-DAPT Trial 🔑

In patients receiving PCI for ACS, Ticagrelor monotherapy after only 1 month of DAPT decreased bleeding WITHOUT a change in ischemic events when compared to traditional year-long DAPT

📸 via Jay Shah

#ACC24 ~~ Ultimate-DAPT Trial 🔑 

In patients receiving PCI for ACS, Ticagrelor monotherapy after only 1 month of DAPT decreased bleeding WITHOUT a change in ischemic events when compared to traditional year-long DAPT 

📸 via @JayShah_MD
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Lochan Shah, MD(@lochanshahmd) 's Twitter Profile Photo

A FANTASTIC summary of . Most excited about REDUCE-AMI, ULTIMATE-DAPT, & CRESCENT - Looking forward to seeing how these might change practice. Particularly excited about MAD devices - now we need longer term fup + resources on the best devices to recc to pts.

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EHJACVC Editor-in-Chief(@EHJACVCEiC) 's Twitter Profile Photo

Look and you will see, look again and you will see more. 💎

ULTIMATE-DAPT trial in perspective

Has the time come for guidelines update and the beginning of
doi.org/10.1093/ehjacc…

Marco Valgimigli

Look and you will see, look again and you will see more. 💎

ULTIMATE-DAPT trial in perspective #ACC24 

Has the time come for guidelines update and the beginning of #precisionmedicine ❓
 doi.org/10.1093/ehjacc…
#EHJACVC #cvacute 
@vlgmrc
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إبراهيم الحمود | Ibrahim Alhomoud(@Ibrahim_PharmD) 's Twitter Profile Photo

🆕📢 دراسة مهمة نُشرت يوم أمس تحت عنوان ULTIMATE-DAPT تناولت المدة الزمنية للعلاج بمضادات الصفائح الدموية (DAPT) بعد النوبة/الجلطة القلبية وتركيب الدعامات.

هذه الأدوية (DAPT) ضرورية لمنع تكون التجلطات الدموية حول الدعامات، لكن يظل نزيف الدم مصدر قلق عند نوعية معينة من المرضى.…

🆕📢 دراسة مهمة نُشرت يوم أمس تحت عنوان ULTIMATE-DAPT تناولت المدة الزمنية للعلاج بمضادات الصفائح الدموية (DAPT) بعد النوبة/الجلطة القلبية وتركيب الدعامات.

هذه الأدوية (DAPT) ضرورية لمنع تكون التجلطات الدموية حول الدعامات، لكن يظل نزيف الدم مصدر قلق عند نوعية معينة من المرضى.…
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たけまる(@3t3xmaisyokugo) 's Twitter Profile Photo

MI後、元は内服薬0の人結構おるから、そこにプラスグレル始めとしてDAPT+PPI+スタチン場合によってはβブロッカー、ACEiと考えると…SGLT2iの月6000円以上の薬価ってやっぱり効果と対比して考える必要がありますな…🥹

初めてのwin ratio勉強なりました🙇‍♀️本日もお世話になりました🙇‍♀️✨

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