Just updated Genotyphi github.com/katholt/genoty… to now type XDR Typhoid reported by Klemm et al in this paper mbio.asm.org/content/9/1/e0… as 4.3.1.1.P1. Genotyphi can also detect QRDR mutations and type H58 lineages 1/2.

Well done Baker Institute on an Athena SWAN SAGE award! Very proud that both our partners, Baker and Cambridge University DPHPC, are part of Athena SWAN.

PhDone! After handing in the thesis and passing earlier this year, I finally got to graduate yesterday! Long PhD journey but loved (almost) every moment of it 😁 Thanks in particular to my main supervisor @DrKatHolt and the rest of the lab for getting me through!

Was recently told I have high (84th percentile) polygenic risk for coronary artery disease through MyGeneRank study. Was reading a recent paper in JACC Journals using UK Biobank data. @minouye271 JohnDanesh onlinejacc.org/content/72/16/…

Congrats, Kat! Rich & fruitful collaboration over the years with many Wellcome scientists MORU @OUCRU_Vietnam @MlwTrust Wellcome Sanger Institute on enteric infections esp typhoid. @Stephen_oucru Jeremy Farrar Buddha Basnyat VinhChau Nguyen Melita Gordon Nicholas Thomson @T7Hien

Power, false discovery rate and Winner’s Curse in eQTL studies Published @NAR_Open by Qinqin Huang Dr. Scott C. Ritchie @MartaBrozynska @minouye271 academic.oup.com/nar/article/46…

Dame Bridget Ogilvie. Born & raised in NSW, she did her PhD Cambridge University & spent her career studying immune responses to nematodes. In 1991 she became Director Wellcome, playing a key role in facilitating Wellcome Sanger Institute & the Human Genome Project x.com/loleen_berdahl…

I'm recruiting! Bioinformatician to lead the sequence analysis pipelines for 100k M. tuberculosis genomes at EMBL-EBI for CRyPTIC. Great computational resources and team. If you have some of: nextflow, singularity, python, variant calling expertise - call me! 1/n

PhD position (London / Nagasaki / Nha Trang, UK / Japan / Vietnam) PHYLOGENETIC INFERENCE OF PNEUMOCOCCAL TRANSMISSION IN VIETNAM - Exciting PhD opportunity iddjobs.org/jobs/phylogene… via IDDjobs: infectious disease dynamics jobs

#DataScience #10yearschallenge from reddit.com/r/datascience/…

"Despite having virtually identical DNA, the twins did not receive matching results from any of the [five genetic ancestry] companies." cbc.ca/news/technolog…

Anyone curious about the quandaries and ethical concerns around consumer DNA testing need look no further than the all time top threads on the 23andme subreddit reddit.com/r/23andme/top/…

Together with Cambridge University, Baker Institute is intensely researching ways, including genomic risk scores (onlinejacc.org/content/72/16/…) to identify subgroups at high risk of heart attack These subgroups may be efficiently targeted for expensive therapies like PCSK9 inhibitors

Our Australian-Anglo research efforts in genomic risk of heart attack were also wonderfully summarised recently by Liam Mannix 👇👇👇 smh.com.au/national/game-…

We couldn't be prouder of Shu Mei Teo! It's going to be an exciting year to come for us Cambridge Baker Systems Genomics Initiative, with more excellent (if not award-winning) science on the way! DPHPC Baker Institute

We're looking forward to a great crowd!

A fantastic conference coming up👇👇 We'll be there and so should you! 😸

The first paper from my post-doc - check out our thoughts on the value of polygenic risk score (PRS) predictions and their potential for clinical utility! w/ Gad Abraham & @minouye271

Very excited to present the Polygenic Score (PGS) Catalog (PGScatalog.org) at #ASHG19, a new resource to improve accessibility & reproducibility of published PGS! An excellent collab of EMBL-EBI (NHGRI-EBI GWAS Catalog), @cambridge_uni (BHF Cardiovascular Epidemiology Unit at Cambridge) & Health Data Research UK (HDR UK)