BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Our immune system is an evolutionary masterpiece. Every day it protects us from the thousands of different viruses, bacteria and other microbes that attempt to invade our bodies. Without a functioning immune system, we would not survive. One of the immune system’s marvels is its

The seminal paper of Shimon Sakaguchi published in 1995 The Journal of Immunology where he discovered CD4+ CD25+ cells that actively suppress autoimmunity. It was the first time T regulatory cells appeared in the literature. Not all Nobel Prize winning work need to be in glamorous journals.

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗 janelia.org/news/researche…

2025 Nobel Prize laureate in physiology or medicine Mary E. Brunkow was born in 1961. She received her Ph.D. from Princeton University University, Princeton, USA. She is currently senior program manager at the ISB in Seattle, USA. hood.isbscience.org/people/mary-br… #NobelPrize

The impacts of different dietary restriction regimens on aging and longevity: from yeast to humans link.springer.com/article/10.118…

Molecular profiling of adult C. elegans glia across sexes by single-nuclear RNA-seq cell.com/developmental-…

Listening to keynote speaker Nigar Shaji, team leader ISRO Aditya L-1 mission, speaking at a joint #INSA and American Chemical Society session celebrating women in science - speaking on space assets & ISRO’s vision/mission. ISRO has been a leader in encouraging women in science

Saddened to hear of John Gurdon’s passing. A brilliant scientist, generous mentor, and endlessly curious. When he examined my PhD viva in 2006, he’d just come from doing experiments at his bench - at 73. He shaped so many careers, including mine: cam.ac.uk/research/news/…

Catch up on Development presents… webinar on gut development Check out the talks of Surojit Sural Surojit Sural & Swarnabh Bhattacharya Swarnabh Bhattacharya Also, register for our upcoming #DevPres on 15 October: us02web.zoom.us/webinar/regist… thenode.biologists.com/catch-up-on-de…

Meet the tiny superheroes — Acrobeloides Maximus a.k.a. nematodes These microscopic worms can turn filthy lakes crystal clean in just one week! A Gujarat University researcher bred them in jelly-like balls to clean Ahmedabad’s dirtiest lakes — including Kankaria & Virat Sarovar

Congratulations to Ishmail Abdus-Saboor on receiving the NIH Director’s Pioneer Award, celebrating “scientists with outstanding records of creativity.” His lab will explore how the sense of touch can help build relationships. 🫶🧠💡See zuckermaninstitute.columbia.edu/zuckerman-inst…

Well-exercised male mice appear to pass fitness to their male offspring | Science | AAAS science.org/content/articl…

Deep Neural Networks to Register and Annotate Cells in Moving and Deforming Nervous Systems elifesciences.org/reviewed-prepr…

Soil nematodes to the rescue

Great Job - Great Colleagues - Great Science👍 Help us pick the next generation of HHMI Investigators, Freeman Hrabowski Scholars, Hanna Gray Fellows, Gilliam Fellows Relocation to DC is required, perfect for academic PIs looking for their next chapter

Paternal exercise confers endurance capacity to offspring through sperm microRNAs sciencedirect.com/science/articl…

This is a really cool paper! A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging | Science science.org/doi/10.1126/sc…

What if your defense system starts supporting intruders! Our research shows that Mycobacteria exploits host immunometabolites to prolong their life- Tata Institute of Fundamental Research DBS TIFR Mycobacterium Papers Biofilm Papers CellChemicalBiology PLOS Pathogens biorxiv.org/content/10.110…

A bacterial food source for effective laboratory cultivation of the freshwater nematode Plectus sambesii micropublication.org/journals/biolo…