Read our latest Orthopaedic Online article ‘The long road to the register: Stories from the Portfolio Pathway’ from consultant surgeons, Jehan Zaib and Rakesh John, highlighting inspiring journeys of immigrant doctors who overcame immense personal and professional challenges to

A missing puzzle piece in Alzheimer’s and other dementias may be 'modifiable' and right in front of us. This study in Journal of Neurology by Montero‑Odasso and colleagues brings into focus vascular risk factors like high blood pressure, diabetes, obesity, cholesterol, and

Clinical #neurophysiology for #tremor • Tremor vs myoclonus • Tremor in PD vs tremor in atypical Parkinsonian syndromes • Dystonic tremor vs Essential tremor • Essential tremor from Parkinson tremor •(Comorbid) functional tremor prd-journal.com/article/S1353-… IAPRD

When Parkinson’s subtypes just won't stay in their lane, what do you do? Is it time to rethink the clinical phenotypes? For years, we’ve tried to box Parkinson’s into tidy clinical subtypes like tremor-dominant, postural instability and gait subtype (PIGD), and also the

Professor Rockwood four magic numbers 75 - age where everything takes off 72- hours to get the frail older adult turned round in hospital 5- Simplify & prioritise CGA. Mobility, Engagement, Cognition & Function 80/20- the team should be able to address 80% of the care plan.

Cracking the code: The brain's convergent pathway in Parkinson's dyskinesia. Spoiler alert: using folks w/ DBS uncovered a role for the subthalamo-pallidal connectivity in DBS. A freshly published study in Movement Disorders sheds light on the neural mechanisms underlying

Just because it’s called SMALL vessel disease doesn’t mean it doesn’t have a BIG impact!   Small vessel disease (SVD) is a BIG contributor to vascular dementia, along w/large vessel cortical infarcts   Do YOU know all the faces of small vessel disease?   Common imaging markers of

(1/x) ICU Tip: Hypotension after procedures = bleeding until proven otherwise. Here's why we sometimes miss it 👇

Free article June 2025 PRD #Parkinson #cancer #PD Is Parkinson disease a risk for cancer ? Impact of Parkinson's disease diagnosis validity on the association with cancer: A systematic review and meta-analysis IAPRD Read the full review: prd-journal.com/article/S1353-…

New study presents the first blood-based profiling of α-synuclein peptides across three α-synucleinopathies (#Parkinsons, dementia with Lewy bodies & multiple system atrophy #MSA); A distinct NAC domain pattern may reflect unique MSA pathological processes academic.oup.com/braincomms/art…

What happens when there is rust in the brain's wires and cells? We continue to struggle with understanding iron and neuroferroptosis and whether there will be an 'iron age' of the brain and disease? The just published paper in Nature Reviews Neuroscience by Lei, Walker and Layton

How does weather impact Parkinson's? Does living 1-3 miles from a golf course affect your Parkinson's risk? These stories and more in this month's free Fixel Movement Messenger. If you don't follow us Norman Fixel Institute for Neurological Diseases on all our social media channels you are missing our daily

🦴 Testosterone + Exercise After Hip Fracture? Here's What We Know 🏃‍♀️💊 A recent randomised clinical trial, 'Starting a Testosterone and Exercise Program After Hip Injury' (STEP-HI), explored whether adding topical testosterone to exercise rehab could boost recovery in older

APOE4 E4/E4 yields a 60% lifetime risk of #Alzheimers by age 85. E3/E3 does not affect risk. Why the difference? Although amyloid and tau PET look similar, there is a rapid and early Aβ42-to-amyloid conversion in E4/E4, depleting CSF Aβ42 levels. nature.com/articles/s4159…

Plastamination nation: Are plastics fueling a rise in Parkinson’s? The latest piece in the journal Movement Disorders sounds a possibly urgent alarm: the plastics all around us, from microplastics in our food to nanoplastics in our air, may be doing more than polluting the

15 Hard Truths of Psychology and Life: 1.

Our first-ever issue of Continuum dedicated to disorders of CSF dynamics is online and shipping! Why did we decide to dedicate a full issue to these disorders? 1/ 🌊🌊🌊

Cheat codes I know at 40, I wish I knew at 20: 1.

🌶️ Could spice be the secret to staying young? 🧬 A recent study from the China Multi-Ethnic Cohort based in southwest China, found that eating spicy food 3–5 times a week was linked to slower biological ageing, especially in the kidneys and metabolism! 🔥🧡 So, if you’re

What a cracking letter.