Oxygen effectively ⬇ right ventricular afterload in an animal model of acute pulmonary embolism🫀🫁🐷 in this study by Mads Dam Lyhne et al. published in Critical Care Medicine journals.lww.com/ccmjournal/Abs… #translationalresearch #cardiology #PE PERT Consortium Aarhus Uni.hospital

Acute #PE ⬆️RV afterload and ⬇️RV function. Inodilators could theoretically flip those arrows. Soon to appear in Pulmonary Circulation. The Pulmonary Vascular Research Institute Asger Andersen Jacob Schultz Simone Juel Dragsbæk PERT Consortium

Congratulations to professor Jens Erik Nielsen-Kudsk who received the Dansk Cardiologisk Selskab (DCS) research award for his outstanding contribution to cardiovascular science 🏆 You are a huge inspiration to all of us 🎉🍾

You do preclinical #cardiovascular or #cardiac research? Regardless your scope and focus, you should consider #PV loops. See how in JoVE jove.com/video/62661 Jacob Schultz Christian Mortensen Anders Kramer Simone Juel Dragsbæk Asger Andersen Jens Erik Nielsen-Kudsk

Acute #PE ⬆️ RV afterload and ⬇️RV function. Ino-dilators may oppose both but few data exist. We investigated three ino-dilators in PE with beneficial hemodynamic profiles: doi.org/10.1177/204589… Pulmonary Circulation The Pulmonary Vascular Research Institute PERT Consortium Asger Andersen Jacob Schultz Simone Juel Dragsbæk

New directions in pulmonary vascular interventions discussed by Asger Andersen at #ESCCongress 🫁🫀#PE #CardioTwitter Jens Erik Nielsen-Kudsk Jacob Schultz Mads Dam Lyhne Anders Kramer Simone Juel Dragsbæk Julie Axelsen

Mads Dam Lyhne et al: Oxygen Therapy Lowers Right Ventricular Afterload in Experimental Acute Pulmonary Embolism Link: ow.ly/dA4s50G2rsE #CritCareMed SCCM Simone Juel Dragsbæk Christian Mortensen Asger Andersen Fig: O2 effects on RV function

Spoiler alert. Filming with JoVE today in the animal lab. Video on biventricular #PVloops in large animal model will soon appear pubmed.ncbi.nlm.nih.gov/34096927/ Anders Kramer Christian Mortensen Jacob Valentin Hansen Jens Erik Nielsen-Kudsk Jacob Schultz Simone Juel Dragsbæk Asger Andersen

Massive #PE completely obstructing the main pulm artery -> cardiac arrest. 💔 “luckily” it was just in our realistic closed-chest porcine model 💪💉🐖 See more: pubmed.ncbi.nlm.nih.gov/32436719/ and pubmed.ncbi.nlm.nih.gov/33870917/ PERT Consortium Jacob Valentin Hansen Jacob Schultz Simone Juel Dragsbæk

In animal models 🐖🐑🐁 of cardiovascular diseases ❤️🩸, biventricular #PV loops provide thorough investigation but consider closed chest approach for near-normal physiology. See our approach: pubmed.ncbi.nlm.nih.gov/34096927/ JoVE #PE #hemodynamics #research

Thank you Danish Cardiovascular Academy for an amazing #dcasummermeeting23 ☀️ We already look forward to next year’s meeting 🫀

Excited to share our work on developing a porcine model of #ChronicThromboembolicPulmonaryDisease 🐖🫁🫀 Mads Dam Lyhne Jacob Valentin Hansen Lina Karout Jens Erik Nielsen-Kudsk Asger Andersen Department of Cardiology Research AUH Aarhus University authors.elsevier.com/a/1hppdBEfCrHO9

🫀 New publication in Thrombosis Research by Simone Juel Dragsbæk et al. A porcine model of #ChronicThromboembolicPulmonaryDisease was developed🐖🫁 Autologous emboli was used, and showed resemblance to human #CTEPH in chronic clot formation 🩸🔬 link: sciencedirect.com/science/articl…