Out now in Thrombosis Research
Our study showing the impact of allele-selective silencing of von Willebrand factor based on a single nucleotide allelic difference in VWF:
1) Thrombosis development is decreased
2) Bleeding times are not prolonged
sciencedirect.com/science/articl…

Thrilled to share our editorial in Thrombosis Research with Azita Talasaz about use of DOAC💊 after bariatric surgery

➡️DOACs: A perfect fit for patients with bariatric surgery?
Université Paris Cité Médecine Hôpital européen Georges-Pompidou AP-HP
sciencedirect.com/science/articl…

It’s #HeartMonth !
♥️ Health = 🧠 Health
Important null results from the Cardiovascular Health Study. Procoagulant factors related to CVD are not related to #dementia . UVM Larner Med UVMHeartBrain
Thrombosis Research
tinyurl.com/4m6bc4vv

💊 Réal life results of direct-acting oral anticoagulants recommended-dose in #obese vs normal-weight patients with venous thromboembolism sciencedirect.com/science/articl… manuel monreal

☠️Prognosis after cerebral venous #thrombosis : Mortality during initial admission and at 30 days and one year after discharge in a large Canadian population-based cohort sciencedirect.com/science/articl…

🫀Intra coronary non-rtPAs and small molecules may be effective for adjunctive therapy to percutaneous intervention,particularly in patients with longer #ischemia periods. #review sciencedirect.com/science/articl…

Fibrinogen and platelets appear to be the drivers of #leukemia associated coagulopathy in the pediatric population, suggesting the utility of using CCTs and #ROTEM in this population sciencedirect.com/science/articl…

This study demonstrates that inadequate response to #aspirin occurs in approximately 38 % of patients undergoing specific high-risk #congenital cardiac procedures using the dosing practice of a national centre. sciencedirect.com/science/articl…

sciencedirect.com/science/articl…

Thrombocytopenia is a cardinal symptom of hantavirus-induced diseases including #Puumala virus (PUUV)-induced hemorrhagic fever with renal syndrome, which is associated with impaired #platelet function, bleeding manifestations and augmented thrombotic risk sciencedirect.com/science/articl…

Immune #thrombocytopenia
The varying degrees of responsiveness to corticosteroid treatment can be attributed to different profiles of basic FGF and TMAO that might be related to overburdened oxidative stress and inflammasome. #microbiota sciencedirect.com/science/articl…

Compared to warfarin, #DOAC reduced the risk of major bleeding🩸 and any serious adverse event in patients after Left atrial appendage occlusion. #review and meta analysis
sciencedirect.com/science/articl…

Thrombocytopenia is a cardinal symptom of hantavirus-induced diseases including #Puumala virus (PUUV)-induced hemorrhagic fever with renal syndrome, which is associated with impaired #platelet function, bleeding manifestations and augmented thrombotic risk sciencedirect.com/science/articl…

Immune #thrombocytopenia
The varying degrees of responsiveness to corticosteroid treatment can be attributed to different profiles of basic FGF and TMAO that might be related to overburdened oxidative stress and inflammasome. #microbiota sciencedirect.com/science/articl…

Compared to warfarin, #DOAC reduced the risk of major bleeding🩸 and any serious adverse event in patients after Left atrial appendage occlusion. #review and meta analysis
sciencedirect.com/science/articl…

The CPES score has acceptable C-statistic, excellent specificity, and low positive predictive value for identification of hemodynamic deterioration in normotensive patients with #PE in patient from PROTECT. sciencedirect.com/science/articl…

#VTE patients are treated with a heparin nomogram including fixed-dose titration boluses to correct subtherapeutic #heparin correlation values
The bolus dose often exceeds the recommended loading dose in #underweight patients

sciencedirect.com/science/articl…

🪐 Observations in space as in microgravity studies on Earth, suggest effects on blood flow stasis, #coagulation , and vascular function.
In this article, the related literature on thrombotic disease in #space is reviewed sciencedirect.com/science/articl…

sciencedirect.com/science/articl…

❌Worrisome thoughts
❌hypervigilance around symptoms, ❌uncertainty of illness
Are experienced by patients with #PE but not covered by Patient-reported outcome measures in studies sciencedirect.com/science/articl…