How to become expert at thing: 1 iteratively take on concrete projects and accomplish them depth wise, learning “on demand” (ie don’t learn bottom up breadth wise) 2 teach/summarize everything you learn in your own words 3 only compare yourself to younger you, never to others

friends are not incidental to a good life; they’re essential to one

sleep is crucial for daily energy, healthy skin, stable moods, and maximum brainpower. take that nap. 🥱

if you think someone is normal, you don’t know them very well. normalcy is a fiction.

its impossible to overstate the difference between a 7/10 doctor and a 10/10 doctor. its not a marginal improvement, they are not even in the same ball park. just spent 2 years in constant pain, nearly debilitating, before finally finding a doctor with a path towards recovery

life changes very fast. it can changes in an instant. you sit down for lunch and life as you know it ends.

“the violence built into the system never counts as violence but the violence of resistance is always considered violence.” — -

it always takes longer than you expect, even when you take into account the hofstadter's law

We are often guilty of confusing quantity for quality – a bad habit from our “more-is-more” consumerist culture.  But history shows that going bigger can backfire spectacularly. bit.ly/44EykZ0

I'm constantly irritated that I don't have time to read the torrent of cool papers coming faster and faster from amazing people in relevant fields. Other scientists have the same issue and have no time to read most of my lengthy conceptual papers either. So whom are we writing

Who do you call when you need to design novel, potent nanobodies vs a pathogen? The virtual lab of A.I. agents nature James Zou Kyle Swanson nature.com/articles/s4158…

do more and more with less and less until eventually you can do everything with nothing.

some absences keep their shape.

"Breaking news! 📰 Bugando Medical Centre's Neurology Unit successfully thrombolysed its 1st stroke patient! 👏 Huge congrats to the Stroke MDT team & thanks to the World Stroke Org & Boehringer Ingelheim for their support! 💡 #StrokeCare #Thrombolysis #BugandoMedicalCentre

A few more interesting things looking at the OpenAI study in Kenyan health clinics with Penda Health 1) the baseline level for clinical errors in treatment seems really high at 50%+ - my guess is that this is probably from rampant antibiotic use for everything (they even give

#TIL of Fermi estimation: looking up key quantities of what is known , and using upper and lower bounds for better predictions.

in contemporary, highly complex systems it is no longer viable—or even desirable—to manage by prescribing fixed end‑states (“predicted goods”).  why? substack.com/home/post/p-16… via Indy Johar

i couldn't, and still can't, understand this deeply unattractive combination of entitlement and self-pity.