Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile
Shenhav Shemer Lab

@shenhav_lab

The Laboratory for #Muscle Biology: Deciphering the Molecular Mechanisms that Control #CellSize | Putting the Brakes on #MuscleWasting in #Aging or #Disease.

ID: 1422130116243730435

linkhttps://cohens.net.technion.ac.il/ calendar_today02-08-2021 09:43:26

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Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

Thank you so much for the kind words! I am truly honored to have had the opportunity to deliver a keynote lecture at the VMN Symposium! Looking forward to future collaborations and discussions within the scientific community.

the paper link (@the_paper_link) 's Twitter Profile Photo

Trend up+119: Urzi A, ..., Gouti M (Nat Commun) __Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells__ thepaperlink.com/:38114482

Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

Excited to announce the launch of the new DREAMS consortium website: dreamshorizon.eu/team/. We are dedicated to tackling five neuromuscular disorders, including DMD. Proud to contribute to this significant scientific initiative!

Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

Inhibition of 26S proteasome activity by α-synuclein is mediated by the proteasomal chaperone Rpn14/PAAF1. pubmed.ncbi.nlm.nih.gov/38415292/

Siniša Hrvatin (@hrvatin_sinisa) 's Twitter Profile Photo

We are recruiting a technician! Our lab studies the biology + applications of hibernation-like states with focus on neuroscience. Position is ideal for college grads interested in working largely independently for two years ahead of pursuing a PhD or MD. wibr.wd1.myworkdayjobs.com/en-US/WIBR-Car…

Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

Thrilled to share that our paper showing how tissues regulate #proteasome content in vivo is now accepted for publication Journal of Cell Biology! Congratulations to our talented postdoc Jennifer Gilda (now in Genentech) and PhD student Dharanibalan for their remarkable work! #muscle 📷

Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

I'm honored to echo the sentiment of this tweet, as I too had the privilege of being a speaker and session chair at this excellent conference on Muscle and Exercise Physiology. I would like to thank Prof. Boris Shenkman for including me.

Rockefeller U. Press (@rockupress) 's Twitter Profile Photo

In Journal of Cell Biology, Gilda et al. Shenhav Shemer Lab show that, in response to catabolic stimuli, muscle cells boost #proteasome levels by inducing proteasome subunit genes & assembly chaperones in a two-phase program controlled by multiple transcription factors hubs.la/Q02xLTxH0

In <a href="/JCellBiol/">Journal of Cell Biology</a>, Gilda et al. <a href="/Shenhav_Lab/">Shenhav Shemer Lab</a> show that, in response to catabolic stimuli, muscle cells boost #proteasome levels by inducing proteasome subunit genes &amp; assembly chaperones in a two-phase program controlled by multiple transcription factors  hubs.la/Q02xLTxH0
Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

Thank you to Journal of Cell Biology for spotlighting our latest paper on regulation of #proteasome content in vivo! Special thanks to our collaborators, Soyeon Park (University of Colorado Boulder) and Yael Mandel-Gutfreund (Technion, Israel) for their invaluable contributions to this work.

Journal of Cell Biology (@jcellbiol) 's Twitter Profile Photo

Proteasome gene expression is dependent on both PAX4 and α-PALNRF-1. Findings from Gilda et al. Shenhav Shemer Lab show that PAX4 and α-PALNRF-1 represent new therapeutic targets to inhibit proteolysis in catabolic diseases (e.g., type-2 #diabetes, #cancer). hubs.la/Q02xLDdd0

Proteasome gene expression is dependent on both PAX4 and α-PALNRF-1. Findings from Gilda et al. <a href="/Shenhav_Lab/">Shenhav Shemer Lab</a> show that PAX4 and α-PALNRF-1 represent new therapeutic targets to inhibit proteolysis in catabolic diseases (e.g., type-2 #diabetes, #cancer). hubs.la/Q02xLDdd0
Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

I am deeply honored to be part of the DREAMS project and to collaborate with such a remarkable team of scientists on this groundbreaking research initiative!

Shenhav Shemer Lab (@shenhav_lab) 's Twitter Profile Photo

I was honored to speak at Ilan Ramon International Space Conference, Israel Space Agency 🇮🇱. Inspiring lectures, brilliant scientists, and great connections. Grateful to be part of such a groundbreaking community! ws.eventact.com/ilanramon2025/… #SpaceScience #IlanRamonConference #Inspiration

Matthew S. Alexander (@matt_muscle_guy) 's Twitter Profile Photo

Congrats to Stainier Lab and colleagues for this interesting new nature manuscript: Transcriptional adaptation upregulates utrophin in Duchenne muscular dystrophy. #DMD tinyurl.com/4ky93z67

RC Rajashik (@iamrajashik) 's Twitter Profile Photo

Sunita Williams and Butch Wilmore experienced zero gravity in space, accelerating their bone loss. After 9 months in microgravity, their bodies have lost balance. On returning to Earth, they won’t be able to stand immediately due to muscle atrophy. [ICSP] #sunitawilliamsreturn

Sunita Williams and Butch Wilmore experienced zero gravity in space, accelerating their bone loss. After 9 months in microgravity, their bodies have lost balance. On returning to Earth, they won’t be able to stand immediately due to muscle atrophy. [ICSP]

#sunitawilliamsreturn
Craig A. Goodman (@craigagoodman1) 's Twitter Profile Photo

Activin A is deeply involved in the progression of sarcopenia and leads to poor prognosis in lung cancer patients nature.com/articles/s4159…

Samrat Chakraborty 🇮🇳 (@iamsamrat96) 's Twitter Profile Photo

🚨 Thrilled to share our new review is out in The FEBS Journal. We discuss fiber-type–specific strategies to combat muscle atrophy. Grateful to Prof Shenhav Shemer Lab for mentorship and support. Excited to see how these insights shape future therapies. #muscle tinyurl.com/3pff8d94