Fast variance component analysis using large-scale ancestral recombination graphs biorxiv.org/cgi/content/sh… #biorxiv_genetic

A scalable approach for genome-wide inference of ancestral recombination graphs biorxiv.org/cgi/content/sh… #biorxiv_genetic

Thrilled that our pioeering work by Anouk Janssen et al. is now live at Nature Communications (nature.com/articles/s4146…)! We built a bridge between two fields: Preimplantation genetic testing (PGT) for nuclear DNA and for mitochodial DNA & coined PGT for aneuploidy origin (PGT-AO).

עבודות פיתוח מסיביות בבית העלמין הצבאי בהר הרצל - חופרים קברים אני מניח. ביבי דואג לנו עד הסוף.

Population Genomic Scans for Natural Selection and Demography A review by Matthias Steinrücken et al go.shr.lc/3yTefkU

Excited to share our new work on the common and rare variant genetic architecture of cognitive ability across childhood and adolescence, using data from Children of the 90s, UCL Centre for Longitudinal Studies, and UK Biobank. medrxiv.org/content/10.110…

Trending in sports once again this year, wow

This month's issue of Archaeology Magazine has a wonderful series of articles about ancient DNA and the human past, weaving together the many allied fields involved in such research. We are so grateful for their coverage of the dynamic population of ancient Rome!

The bioRxiv search seems to be down - did anyone else notice? Richard Sever

The Azrieli Foundation provides a very generous salary for two years of postdoctoral research in Israel. Please see the link for details. If anyone interested please DM/email me. Complicated times here, I know, but at least never boring 🤷 azrielifoundation.org/fellows/intern…

🔹 New article online 🔹 PES should only be offered to patients within a research context until more is known about the balance of benefits and harms, authors of ESHRE-supported review conclude. Find the full article here 👇 focusonreproduction.eu/?p=1826&utm_so…

Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery: a multi-ancestry study in 10 960 individuals from 9 biobanks medrxiv.org/cgi/content/sh… #medRxiv

Stabilising selection enriches the tails of complex traits with rare alleles of large effect biorxiv.org/cgi/content/sh… #biorxiv_genetic

Scroll to the replies for an excellent (and passionate!) discussion on the value of ancient (vs existing modern) genomes for learning about recent demographic history.

A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release journals.plos.org/plosone/articl…

1/13 Our evaluation of the UK Biobank Polygenic Risk Score (PRS) Release (Version 2, May 2024) is now out in @plosone (doi.org/10.1371/journa…), with Genomics plc UK Biobank @genomicsEngland. The traditional tweetorial/Xorial follows…

Estimation of demography and mutation rates from one million haploid genomes biorxiv.org/cgi/content/sh… #biorxiv_genomic

Very important issue at the moment. Listen to Shai Carmi and Heidi Mertes and be correctly informed when you get the suggestion to use polygenic embryo screening on your patients