Scleroderma Lab Leeds
@sclerodermalab
The Scleroderma Research Programme is a patient oriented multidisciplinary research team comprising basic, translational and clinical research on Scleroderma
ID: 1168228680902029312
01-09-2019 18:26:49
23 Tweet
71 Followers
44 Following
In our paper out today in Science Translational Medicine by Steven et al, we show that stimulating the body’s immune defence at the mosquito bite is highly effective at suppressing infection with many distinct viruses. Works for alpha-, flavi-, and bunya-viruses. 1/n stm.sciencemag.org/content/12/527…
New pre print from the group in collaboration with Clive McKimmie (VHIT) 🦟🦠🐁
The Lancet Respiratory Medicine REVIEW: Randomised controlled trials in #SystemicSclerosis: patient selection and endpoints for next generation trials thelancet.com/journals/lanrh… #LancetRheumatology #RareDiseaseDay #SSc
LTHT Rheumatology COVID immunosuppressants 31 3 20 youtu.be/ZGROdmpcyj8 via LTHT People Chapel Allerton Hospital CSU NIHR Leeds BRC SRUK | Scleroderma & Raynaud's UK Scleroderma Lab Leeds
New work from the group just published in ArthritisResTher. We have shown HOTAIR regulates the expression of the sonic hedgehog transcription factor GLI2 in scleroderma fibroblasts. A great collaboration with the Natalia Riobo-Del Galdo. arthritis-research.biomedcentral.com/articles/10.11…
Check out our latest paper in Rheumatology & Rheumatology Advances in Practice where we show the intracellular chloride channel 4 (CLIC4) plays a role in SSc fibroblast activation. This is one of the first examples of an ion channel playing an important role in the disease. academic.oup.com/rheumatology/a…
I am delighted to share the approval of Actemra for SSc related ILD. The FDA was pragmatic and approved the medication, based on large clinically meaningful effect on lung function. #scleroderma #hope U-M Department of Internal Medicine Genetec Inc. gene.com/media/press-re…
#ResearchHighlight | Targeting pDCs in SSc #SystemicSclerosis #scleroderma #rheumatology Read the original research from Scleroderma Lab Leeds Annals of the Rheumatic Diseases here bit.ly/3kWr0Q1 Read our #news story here go.nature.com/2OCLtxq