Inflammation and dysfunction of the lining of blood vessels—the endothelium—is the basis for many of the cardiovascular complications of Covid. A new, solid review here nature.com/articles/s4140…

Convergent evolution UPDATE 10/19. More converging BQ.1.* sublineages and an interesting pipeline (CA.4, BN.4, BN.3.1, BL.1.*) Eric Topol T. Ryan Gregory 🇨🇦 Eric Feigl-Ding Ewen Callaway Cornelius Roemer Federico Gueli 🏳️ Florian Krammer Kai Kupferschmidt Denise Dewald, MD 🗽 @mildanalyst Roberto Burioni

#LongCovid is a microvascular disease. “The first thing to go are your smallest blood vessels… This will not show up on x-ray or CRP test.. your labs will look completely normal”

#OTD 15 years ago, history was made in the form of a handshake🤝 On Oct. 25, 2007, two women commanders, Peggy Whitson and Pamela Melroy, shook hands in space. Since then, women’s representation on space crews have increased significantly. go.nasa.gov/3swjAro

Someone asked for a collection of my COVID threads in advance of (US) Thanksgiving in case they want to share some info with family members. Here you go (links to Twitter thread and Threadreader). 🧵

Returning to free Covid tests in the US 👍. They'll come in handy with upcoming gatherings, especially with the current wave gaining steam. Ordering starts tomorrow politico.com/news/2022/12/1…

Join The AMR Narrative & CIDRAP for a Tweetchat about #AntimicrobialResistance & #RareDiseases on #RareDiseaseDay Our panel includes Rare Autoinflammatory Conditions Community - UK®️ AboutFace Ella Balasa Ataxia and Me CIO 1184030 Patient Worthy Dysautonomia Support South Africa ChiariTracy Joel Nelson Rare Diseases South Africa #theAMRnarrative

Today Chandra is pointed into Draco. Nearby in the sky is NGC 6338 — 2 groups of galaxies slamming into each other at about 6.4 million kilometers per hour. One of the most violent collisions of this type ever seen, it's producing temperatures near 20 million degrees Celsius.🔥

Lyrebirds are Australian birds most notable for their superb ability to mimic natural and artificial sounds from their environment (and other environments, if it's the case) [full video by Saeed Lajami: buff.ly/2waNvJ3]

Today Chandra is studying Terzan 5, a globular cluster of stars located about 19,000 light-years from Earth. Globular clusters are roughly spherical collections of tens of thousands to millions of stars that are tightly bound by gravity and found in a wide variety of galaxies.✨

I don’t usually post personal news but Clinicians have told us to pull every lever. Our daughter has with #dipg Brain cancer. There is no cure and typically 9m life expectancy. If anyone knows of trials then please get in contact! #braincancer #childrenscancer Cancer Research UK

For all those on Earth's Northern Hemisphere, goodbye winter — hello spring!💐 Spring officially begins today at 5:24 pm EDT. Here's a pretty picture of the Tycho supernova remnant. We'll be outside if you need us.😎

Today Chandra is studying E0102, a supernova remnant produced by the explosion of a massive star in a nearby galaxy. Most of the oxygen in the Universe is synthesized in massive stars. The amount of oxygen in this ring alone is enough for thousands of solar systems.😮

On April 3, you will meet the team of astronauts flying to the Moon on the #Artemis II mission. These explorers will pave the way for future lunar landings and our next giant leap — human exploration of Mars. youtube.com/live/mua1Lysc_…

A thousand pleases: Please watch and share this brilliant simple video from Long COVID Physio sharing guidance on how to do Long Covid rehabilitation **safely** and trying to undo some of the damage caused by people pushing inappropriate exercise as rehabilitation.

The Soyuz 3rd stage from today's Glonass navsat launch reentered SE of Tasmania. Here's the reentry warning area (white) and my estimate of the 3rd stage suborbital track (orange). Yes, I know they don't quite match up, I did a rush and approximate job, but it gives you the idea

Long-range transmission of SARS-CoV-2 is the dominant mode: academic.oup.com/pnasnexus/arti…

Fantastic paper on safe indoor air for kids in school by A/Prof Donna Green UNSW on impact of air purifiers in #schools with UNSW Engineering colleagues. Natural ventilation w HEPA filters is most effective way to reliably improve indoor air quality. iopscience.iop.org/article/10.108…

Tracy Chapman, who has not performed in public in years, performs "Fast Car" with Luke Combs at the #Grammys: