"Development and application of a biophysical platform for the identification of fragments for the development of SETD8 ligands" (P70) DCF-SCI #NPCF13 #DCFSCI #epigenetics

I'm Giuliana Sarno, a PhD student at EpigeneticMedChemLab Università Salerno. My poster (PC_60) is focused on development and application of a biophysical platform for the identification of fragments for the development of SETD8 ligands. Net4Science #PEVM2021 #medchem

Huge congratulations to Giulia Iannelli for brilliantly defending her PhD thesis entitled “Design, synthesis, biological evaluation, and binding studies of small-molecule modulators of PRMTs”. Great job! At EpigeneticMedChemLab we are very proud of you!

"I understand the gravity of being a woman and now a #Nobel laureate in the sciences. There aren't that many of us—yet." Prof. Carolyn Bertozzi on chemistry, mentorship and representation ⬇️

One of my fondest memories of filming Harry Potter was a night shoot on the first film in the forbidden forest. I was 12. Robbie cared & looked after everyone around of him. Effortlessly. And made them laugh. Effortlessly.

An inspiring talk and journey in the world of drug discovery at the 3rd ESMEC Alumni Award ESMEC! And some tips to take always in mind!

ESMEC Poster Prize winner - Giuliana Sarno, University of Salerno (I) Giuliana Sarno

NUDELs are DNA-encoded libraries poised to grow fragments – iterating new options faster practicalfragments.blogspot.com/2023/07/dna-en… Medicinal Chemistry Group - Newcastle Uni Chemical Science Mike Waring Catherine MoSMed CDT

A nice collaboration with Steve Clarke (⁦⁦UCLA Chem & Biochem⁩), Yanzhong Yang (⁦City of Hope⁩) and ⁦Sandro Cosconati⁩ work on the identification of a PRMT7PRMT9 inhibitor, just published in J. Med. Chem. ⁦ACS Publications Bio & Med Chem Content⁩. pubs.acs.org/doi/10.1021/ac…

Our Perspective on NADPH Oxidases, spanning from molecular mechanisms to current inhibitors has just been published on-line (open access) in J. Med. Chem. (ACS Publications Bio & Med Chem Content). Thanks to all the members of EpigeneticMedChemLab involved! pubs.acs.org/doi/10.1021/ac…

Super proud to have shared my work at #NMMC28 with outstanding medicinal chemists! DCF-SCI

EpigeneticMedChemLab welcoming our guest, a visiting PhD student from Freiburg ! Nice to make your acquaintance, Maxi! Alessandra Cipriano Ciro Milite AlessandraFeoli Giuliana Sarno

DMSO-Related Effects on Ligand-Binding Properties of Lysine Methyltransferases G9a and SETD8 (G. Sbardella et al.) Gianluca Sbardella Giuliana Sarno AlessandraFeoli Sabrina Castellano EpigeneticMedChemLab Università Salerno onlinelibrary.wiley.com/doi/10.1002/cb…

Do you know what an ion channel is? In 1998, medicine laureate Roderick MacKinnon succeeded in demonstrating what a potassium ion channel looks like by using x-ray crystallography. This mapping allowed MacKinnon to explain how potassium channel selectivity occurs. #NobelPrize

The EpigeneticMedChemLab will be present, as usual, this time with 4 attendees from the group. Enjoy ESMEC and Urbino, Ben, Ida, Rosy and Giuliana Sarno!