Discover the latest breakthrough in synthetic aryne chemistry! Tabata and Yoshida's work on bromothiolation of arynes introduces a novel method to synthesize o-bromobenzenethiol equivalents. Check it out: pubs.acs.org/doi/10.1021/ac…

Webster Santos lab get together. My amazing co-workers. 🙏👏 Virginia Tech Chemistry Fralin Life Sciences Institute Virginia Tech Science

Last Webster Santos undergrad group meeting presentation last night! 👏Here’s where they are going: Katrina McCarter (@NCStateChem), Owen Beck (@YaleChem), Abigail Agner (gap), Ethan Duerre (@PennDentalMed) & Isabella DeLuca + Long H Nguyen (@VanderbiltChem). Virginia Tech Chemistry

GLP-1 drug rides again.......
Among 51 people with metabolic dysfunction-associated steatotic liver disease (MASH, MASLD) with HIV, 15 (29%) had complete resolution and 30 (58%) had >30% reduction of liver fat
acpjournals.org/doi/10.7326/M2…
Annals of Int Med

Congrats to Webster Santos dept award winners! Mary A. Foutz Nicklas Buchbinder Long H Nguyen Ethan Duerre and Owen Beck. Our lab is well represented. Many thanks for the hard work! Virginia Tech Chemistry

Celebrating our faculty champions that inspire a culture of innovation! Bravo.
🎉Commercialization Champion: Bo Zhang, VT School of Plant and Environmental Sciences
🎉Startup Builder: Webster Santos, Virginia Tech Chemistry
By Example Awards:
🎉Bahareh Behkam, Virginia Tech Mechanical Engineering
🎉Robert Gourdie, Virginia Tech Biomedical Engineering & Mechanics
bit.ly/3xTZoFR

Successful open house for the VT CDD screening center VirginiaTechCDD. Here’s to more collaborations! Fralin Life Sciences Institute Virginia Tech Science VT Biochemistry

Copper-catalysed asymmetric hydroboration of alkenes with 1,2-benzazaborines to access chiral naphthalene isosteres (Nature Chemistry): nature.com/articles/s4155….

Congrats to the VTCDD poster award winners! #1 Mary Foutz Mary A. Foutz, #2 Abdullahi Jamiu, #3 Emily Krinos em. Congrats to Webster Santos Kylene Kehn-Hall labs! Special thanks to Fralin Life Sciences Institute Virginia Tech Science for support.

Our annual VT Center for Drug Discovery poster session is in full swing. Check out the amazing work of our students in Hahn Hall south atrium (12-2 pm). Virginia Tech Chemistry Virginia Tech Science VirginiaTechCDD

Check out our collaborative work with Todd Marder (Universität Würzburg #UniWürzburg) and colleagues. Organocatalytic diboration of enynes. Nice work Nicklas Buchbinder. Check it out at Chemistry. Virginia Tech Chemistry Virginia Tech Science

Preprint work with Kevin Lynch UVA Pharmacology. We developed #Spns2 inhibitors and showed efficacy in #MultipleSclerosis mouse model + no cardiac & auditory side effects. Biomarker=lymphopenia. Builds a case for drugging #Spns2 . Virginia Tech Chemistry Virginia Tech Science
biorxiv.org/content/10.110…

Your annual reminder to avoid azide reactions in DCM
#ChemTwitter #ChemSafety
pubs.acs.org/doi/full/10.10…

17 years in the making..

We are super excited to finally achieve alcohol-alcohol cross-coupling enabled by the powerful SH2 radical sorting! Great work Jerry, Nick, Jay, James, Colin and Robert. Big shout out to our collaborator Jesus from Janssen Spain.

science.org/doi/full/10.11…

Photoinduced Decarboxylative Borylation of N-Hydroxyphthalimide Esters with Hypoboric Acid (J Org Chem/Org Lett): pubs.acs.org/doi/10.1021/ac….

Terminal C(sp3)–H borylation through intermolecular radical sampling (Science Magazine): science.org/doi/10.1126/sc….

Enantio- and Regioselective Dihydroboration of Enals (ACS Catalysis): pubs.acs.org/doi/10.1021/ac….

Check out Nicklas Buchbinder & Rose Campbell's paper in ACS Med Chem Lett ACS Publications Bio & Med Chem Content. New class of 3-Substituted-2(5H)-Oxaboroles as antifungal agents. Collaboration work with Mevers Lab. Congrats to all 🙌 Virginia Tech Chemistry pubs.acs.org/doi/10.1021/ac…