Sibeprenlimab for IgA Nephropathy

Urea, also known as *carbamide*, is a safe, useful compound with a significant history. It is a naturally occurring molecule that is produced by protein metabolism and found abundantly in mammalian urine.

Contraindications for conserving a catheter in CRBSI 📍Hemodynamic instability 📍Exit site infection 📍Metastatic foci (IE, OM etc.) 📍Prosthesis in situ 📍Staph aureus/Candida on cultures (Difficult to eradicate bugs).

[1/26, 10:44 PM] sandeep paryani: Even lose methotrexate (5-15 mg/week) should not be prescribed in dialysis patients with rheumatoid arthritis ❌ 👹Can lead to profound myelosuppression.

DMARD of choice in RA 🦴 Methotrexate & renal correction 🫘 🔷 CrCl >50 mL/minute: No dose adjustment necessary. 🔷 CrCl 10 to 50 mL/minute: Administer 50% of dose. ♦️ CrCl <10 mL/minute: Avoid use