Sarah Aitken (@s_j_aitken) 's Twitter Profile
Sarah Aitken

@s_j_aitken

@CR_UK Clinician Scientist @Cambridge_Uni •
Group Leader @aitken_lab @MRC_TU •
Consultant Pathologist @CUH_NHS •

#GenomicPathology
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linkhttps://www.aitkenlab.org calendar_today09-12-2012 14:48:52

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Sarah Aitken
@s_j_aitken

3 months ago

Clustered mutations occur more frequently than expected, and translesion synthesis (TLS) drives collateral mutagenesis on both the leading and lagging strands. SNVs are clustered downstream of deletions (biased towards deletion of T) but upstream of insertions. [4/13]

Clustered mutations occur more frequently than expected, and translesion synthesis (TLS) drives collateral mutagenesis on both the leading and lagging strands. SNVs are clustered downstream of deletions (biased towards deletion of T) but upstream of insertions. [4/13]