Excited to finally see ExpiMap out Nature Cell Biology - led by @Mohlotf & Sergei Rybakov, we inform single-cell embeddings by pathway priors (+ newly-learnt ones). This allows for biologically understandable components in the latent space and program queries. nature.com/articles/s4155…

🚨 ONLINE Nature Genetics 📰 Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity 🧑‍🤝‍🧑 YukinoriOkada Atsushi Kumanogoh and team 👇🏿 go.nature.com/3oGY84k

Our new paper is finally out! "Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity" Nature Genetics (nature.com/articles/s4158…)

📣COVID-19 single-cell RNA-seq & host genetics of Japanese led by Ryuya Edahiro is finally online at Nature Genetics 🎉. Innate immune cells have critical roles in COVID-19 severity. Thank for the great team !! nature.com/articles/s4158…

～ 今年もやります、遺伝統計学・夏の学校 ～ 遺伝統計学の理論~実践のハンズオン演習セミナーです(2025/8/29金-31日)🧬💻🏝️ Hybrid形式(会場:東京大学本郷キャンパス). 是非ご参加ください. #bioinfo #gwas #eqtl #singlecell ※ 初学者向け「基礎編」は今回で一旦終了です genome.m.u-tokyo.ac.jp/school_2025.ht…

Our new paper in Nature Genetics!! Single-cell deconvolution of various somatic mutations including mCAs, loss of Y, and mt-heteroplasmy. nature.com/articles/s4158…

Single-cell ＆dynamic eQTL PBMC of Japanese PBMC🧬🩸🖥️. Somatic mutations (mosaic chromosomal alteration; mCA, loss of Y; LOY, mitochondria heteroplasmy) projected to single cell resolution by Ryuya Edahiro Go SATO & team🤼. Now Nature Genetics ㊗️🎉 nature.com/articles/s4158…

Excited to share our whole-genome sequencing study on psoriasis out in Cell Genomics! Looking into rare and structural variants highlighted the disease genetics that conventional GWASs have overlooked. dlvr.it/TMdf1X

WGS structural & rare variant analysis of psoriasis vulgaris identified IFNLR1 3kb deletion SV & risk RV at cercam fol by long-read seq, skin spatial transcriptome, knockout mouse with imiquimod psoriasis model. Lead by Kyuto Sonehara in Cell Genomics🎉 cell.com/cell-genomics/… #WGS

お陰様で三日間の「遺伝統計学・夏の学校」が無事終了しました（通算10回目）🧬🏝️🏫🎉。御参加頂いた皆様とラボメンバーに感謝です🙏。講義資料と演習データを公開します🎁。 ※2023年の公開コンテンツに類似ですが、少しアップデートしています。 genome.m.u-tokyo.ac.jp/school_2025.ht…

Our Platforms & Finalists #ASHG2025🎉🧬 Kyuto Sonehara SV & RV psoriasis risk by WGS: CERCAM as novel risk gene Sugahara K. East Asian GWAS of serum immunoglobulin & subclass for humoral immunity Go SATO Male genetic regulation of germline & somatic Y chr variation shape T2D risk