Everything you've ever wanted to know about #Ferroptosis in Health and Disease! Massive review from many in the field. Happy to have contributed and huge thank you for the leadership from Carsten Berndt / Marcus Conrad The Conrad Lab. 🙂 doi.org/10.1016/j.redo…

🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)

Degrader Tac-opedia 🔘PROTAC: E3 ligase-targeted proteolysis 🔘DUBTAC: Deubiquitinase stabilization 🔘LYTAC: Lysosome-targeted degradation 🔘Trivalent PROTAC: Multivalent E3 ligase 🔘AUTAC: Autophagy-targeted degradation 🔘RIBOTAC: RNA-targeted degradation 🔘RNA-PROTAC:

Timescales in Cell Biology

New preprint! Our latest study identifying how MHC-I is captured by autophagy and targeted for degradation in #PDAC - It all happens at the ER ! Congrats to co-first authors Marine Berquez Alex Li & Matthew Luy. Details below 👇 biorxiv.org/content/10.110…

GLP-1 receptor agonists, which are effective for weight loss, can cause substantial muscle loss. A Comment in The Lancet Diabetes & Endocrinology discusses the effects of GLP-1 receptor agonists on skeletal muscle mass: hubs.li/Q02WgC490

Body and brain must communicate to adapt behavior efficiently. Using the fly, we discover a bidirectional pathway between the fat body and the brain and show that fat body-produced dopamine changes food preference.

SAVE THE DATE!!

A rapid chemical reprogramming system to generate human pluripotent stem cells nature.com/articles/s4158… nature.com/articles/s4158…

Top 5 advances in medicine this week (🧵) 1. The first-in-human use of iPSC-derived CAR-NK cells

instagram.com/p/DExQ0bXzkxO/…

Munich 1938, Europe’s leaders made an agreement that Adolf Hitler could take parts of Czechoslovakia in exchange for a promise that Germany would not engage in further acts of war. Czechoslovakia was not involved in negotiations but had to accept the outcome.

Congrats Tony Hui

Lactate homeostasis is maintained through regulation of glycolysis and lipolysis dlvr.it/TJMzm9

KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors Now KnockTF 2.0 👤🐭🌱🌽 >1400 transcriptomes ~800 TF/TcoF licpathway.net/KnockTF/index.… Go to "Search" for your TF "Quick Search" does not work Nucleic Acids Res 2020

We are thrilled to announce the appointment of Alec C. Kimmelman, MD, PhD, as the next Chief Executive Officer at NYU Langone Health and Dean of NYU Grossman School of Medicine effective September 1, 2025. Learn more: nyulangone.org/news/nyu-lango…

Lactate controls cancer stemness and plasticity through epigenetic regulation dlvr.it/TJwtQM

Sharing our latest review on peptide hormones by Laetitia Coassolo Laetitia Voilquin-Coassolo and Amanda Wiggenhorn Amanda Wiggenhorn in Trends in Biochemical Sciences Trends in Biochemical Sciences Stanford Pathology Free full text: sciencedirect.com/science/articl…

One year ago, I reserved and paid a deposit on two rooms at hyatt Place Princeton through Hotels.com for my daughter's graduation. One day before arrival I learn that @hyatt canceled one room without explanation or recourse. Now am scrambling to find housing. Buyers beware.

Online today in nature - our latest study led by superstar postdoc Gilles Rademaker detailing the role of PSCK9 in driving sterol dependent metastatic organ choice in pancreatic cancer nature.com/articles/s4158… full text available here 👉 rdcu.be/em0VG and thread 👇