RNAseq is commonly performed. We compared N=30 wild-type Bl6 mice to an N=30 heterozygotic knockout with a phenotype, and then downsized. We found you need at least an N= 8-12 to avoid a >50% false positive rate. A 2nd line confirmed the finding. biorxiv.org/content/10.110…

Jeśli nie jest Ci obojętny los Narodowe Centrum Nauki podpisz petycję o zwiększenie finansowania nauki w 2025. Studenci, akademicy, przedsiębiorcy Polska Akademia Nauk KRASP Dariusz Jemielniak A. Gmiterek-Zabłocka petycjeonline.com/list_otwarty_d…

Happy #PolishAmericanHeritageMonth! In October 1608, the first Polish settlers arrived in Jamestown, Virginia. Since 1981, we’ve proudly celebrated the culture, history, and contributions of Polish Americans. Here's to honoring the past and embracing the future! 🇵🇱🇺🇸

Kiss😘of the RNAs Excited to share our work on the significance of a ‘kissing loop’ RNA-RNA interactions in driving RNP granule assembly. nature.com/articles/s4155…

Our focus issue on RNA biology features reviews that explore the many faces of #RNA, diving into the processes mediating the lifecycle of RNA, the regulatory roles of RNA, the importance of RNA in disease, and the technologies used to study RNA. cell.com/molecular-cell…

Phoebe Rice and I developed an outreach module using paper models to share our passion for nucleic acids and structural biology. Now, you can use it too! #UChicagoBMB #structuralbiology #biochemistry #womeninstem Check it out: cdn.rcsb.org/rcsb-pdb/gener…

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

Your mental health matters. Good mental health helps you cope with stress and can improve your quality of life. Get tips and resources from National Institute of Mental Health (NIMH) to help take care of your mental health. go.nih.gov/7B7252U #WorldMentalHealthDay

Come work with us in the Laboratory of Protein Structure (MarcinNowotny lab), aka LSB!

💥Cheeky 'little' update from GencodeGenes v47, almost doubling the number of #lncRNA genes & ~4x more lncRNA transcripts. This was highlighted by Qing Wang when observing the greater quality of our reference-guided de novo TxOme assemblies from deep direct RNA sequencing data

Refreshed look for Tools for Science! arjun-raj-lab.gitbook.io/arjun-rajs-too… Also, given the season, here's my guide for applying to faculty positions: arjun-raj-lab.gitbook.io/arjun-rajs-too…

Beyond thrilled to present our O-MAP—now *published* Nature Methods (!!!) O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵 nature.com/articles/s4159…

www2.rnasociety.org Check it out! The RNA Society 2025 Meeting Site is now live! Registration will open in January The RNA Society Note the fabulous artwork by former Emory Biochemistry Cell & Developmental Biology student Dr. Carly Lancaster- make your plans now to join us in San Diego May 27-June 1, 2025

I am thrilled to see ZhangliSu in the spotlight! 🌟 She’s a brilliant scientist and one of the kindest people I know. 👏 #ScienceHeroes #Inspiration

Genome-Wide Identification of Stable RNA Secondary Structures Across Multiple Organisms Using Chemical Probing Data: Insights into Short Structural Motifs and RNA-Targeting Therapeutics bioRxiv biorxiv.org/cgi/content/sh…

I am organizing a seminar/conference + recruiting speakers. In this blog post, I walk through how I use #AI to augment my intelligence in identifying diverse speakers (+ prevent manels). Try it out yourself: jef.works/blog/2024/11/0… #AcademicTwitter #DEI #Rstats #creativecoding

Thank you Sara Osman NatureStructMolBiol for featuring our two studies on #MALAT1 & #NEAT1 on the Nov cover! Led by Ilias Skeparnias we describe how #lncRNA partially mimic #tRNA structure for their maturation and #mascRNA #menRNA biogenesis. nature.com/nsmb/volumes/3…

Take a look at this amazing work of Cameron Griffiths from Janes Lab at Virginia BME This is what I call the scientific advance! Congratulations 🎉👏

Using #SystemsApproaches, Janes Lab, Lazzara Lab, et al. sasco.virginia #NCICSBC are investigating subcellular adaptations that take place to subvert stresses that occur in response to cancer-causing #mutations. cancer.gov/about-nci/orga…

If you ever wondered why #SystemsBiology, this movie is for you! Prepared by Sarah Maddox Groves from Janes Lab Virginia BME sasco.virginia youtu.be/rmuj1cyIn44?si… WHAT is systems biology? WHY do we need systems approaches in cancer? HOW do systems approaches get used in the clinic today?