Sebastian Roemer
@roemerseb
Clinician Scientist at Franzmeier-Lab ISD, Munich; Neurologist at LMU: Munich University Clinic; Neuroimaging & Cognition; 4R-Tauopathies; Alzheimer’s Disease;
ID: 1187202307
16-02-2013 19:20:48
36 Tweet
143 Followers
170 Following
Intresting short article in Nature Medicine discussing the decline in clinical academics in the UK and US. Another issue, not discussed, is the failure to recognise all the components of the job equally, clinical/research/teaching. The interests of Universities and the NHS are
Super happy to share our new work out in Nature Communications, showing that synaptic changes accelerate amyloid-related tau accumulation and spread in #Alzheimer's disease. Many thanks to Michael Schöll and many others! ISD Research, Göteborgs universitet / University of Gothenburg doi.org/10.1038/s41467…
If you wanna learn of a new way of how Amyloid-beta promotes tau spreading via neuronal hyperactivity come see my poster number 44 at #HAIconference Nico Franzmeier
Amyloid-positive people with high CSF GAP-43, a synaptic marker, accumulated tangles faster than those with low GAP-43. Tangles spread through connected brain regions, supporting the idea that tau travels via neural pathways. Uni of Gothenburg Universität München ow.ly/ZKhY50QrQc4
Great work Maura Malpetti and others and great seeing you at HumanAmyloidImaging in Miami. #HAI2024 The replication aspect of this work is what I particularly like!
💡New publication by Nico Franzmeier in Nature Communications on the importance of synapses in the spread of tau 👇 🔗Read a summary of the research on our website: synergy-munich.de/news-events/ne…
Thrilled to share our new Preprint on the cellular origin of PI-2620 in 4R tauopathies, including PET to autopsy data animal models, cell-sorting and much more. Key message: PI-2620 does capture 4R tau. Thanks to MatthiasBrendel Günter Höglinger and many more! biorxiv.org/content/10.110…
🚨publication alert: image derived input function for [18F]PI-2620 quantification. An elegant way to perform kinetic modeling before selecting an appropriate reference tissue. Many thanks to Nico Franzmeier Günter Höglinger Johannes Sebastian Gnörich Johannes Levin Sebastian Roemer link.springer.com/article/10.100…
First autopsy validation of PET tracer PI-2620 in #progressivesupranuclearpalsy confirms it binds 4R tau deposits. Universität München ow.ly/FJkn50RTzmP
New Paper alert doi.org/10.1002/mds.29…: We compared MRI measures (volumetric/planimetric/staging systems) to track atrophy in PSP. Brainstem/midbrain volume tracked atrophy progression best, suggesting usability as surrogate endpoints. Günter Höglinger Sebastian Roemer Johannes Levin
There it is officially - still can’t believe I get to publish in my favorite journal! As a Clinician Scientist ideas are plenty and time is limited, and only with the massive support of Nico Franzmeier MatthiasBrendel and Günter Höglinger it was possible to do both: clinic + science
Biological definition of Parkinson’s disease is approaching 🚀 will this be „ATN“ for PD? much to do for the neuroimaging community! Many thanks to Silvia Morbelli Nathalie Albert Günter Höglinger and the EANM NIC! link.springer.com/article/10.100…
Happy to be part of this cool cooperative project between Cambridge Maura Malpetti and the Munich 4R tauopathy team lead by Nico Franzmeier Johannes Levin MatthiasBrendel and Günter Höglinger Stay tuned for the follow-up project on how tau, microglia and neuronal dysfunction are linked
Cool imaging session with progressive out-of-the-box new research from our lab Nico Franzmeier and others Jake Vogel hosted by RikOssenkoppele at #AAIC24 with tons of thought provoking questions in Q&A
