Special issue on AI in infectious disease research thelancet.com/series-do/arti…

Genome language models can generate new, high-fitness bacteriophages! Samuel King Claudia Driscoll @_david_li Daniel Guo Aditi Merchant Garyk Brixi Max Wilkinson Brian Hie

🚨📝 New work via The Pandemic Institute now preprinted! We took 19000 sequences of avian influenza virus and trained machine learning models on >40000 genomic/proteomic features - the resulting model can predict zoonotic potential with AUC=0.95. More below! biorxiv.org/content/10.110…

Scientists have created the first ever viruses designed by AI, and they’re capable of hunting down and killing strains of E. coli go.nature.com/4mppvIi

We asked ourselves what could we do if we worked cooperatively as a team to create a single model that could design any biomolecular interactions. Yesterday, we reported details of RFdiffusion3, the next step towards building functional proteins straight from the computer.

We may have been making a lot of progress in genome design, but we are not done with protein design just yet lol

Genome-resolved metagenomics reveals microbiome diversity across 48 tick species | Nature Microbiology nature.com/articles/s4156…

Today, we report Germinal, a method for efficient de novo antibody design, with Santiago Mille and Xiaojing Gao. Germinal achieves success rates of 4-22% across diverse epitopes. We make the work fully open, without doing lame things like posting a preprint without methods. 🧵

Thrilled to share that today we report our human protein interactome in Science Magazine! Predicting which pairs of proteins in the human proteome is a great challenge due to the shallow eukaryotic evolutionary signals but hugely important to understand. science.org/doi/10.1126/sc…

'Over the last 16 years, it’s really been the greatest privilege to lead this remarkable institution’ Our Principal Anton Muscatelli shares a message ahead of his retirement next week. ‌‌Anton reflects on his time at UofG & thanks the community for all their hard work & support.

New exciting resource published!! The Viro3D paper is out, describing our comprehensive database of predicted virus protein structures! 💻🧬 Work with MRC-Uni of Glasgow Centre for Virus Research 's Ulad Litvin, Joe Grove, Alex Jack, Robertson and Joseph Hughes embopress.org/doi/full/10.10…

For many years, the world chased rumors of a lab leak, worried about a cover-up. Then in March 2023, new genetic data emerged that told a different story. But was the world ready to accept the unequivocal conclusions? A thread on probably the most critical chapter 1/

Vaccines worked. Vaccines still work. Vaccines will work. In the past, the barrier was scientific. The new barrier is increasingly a failure of leadership.

If the U.S. NIH budget had been 40% smaller—similar to cuts proposed in the FY2026 budget—how would that have affected the medicines we enjoy today? In a new #SciencePolicyArticle, researchers present an analysis of a hypothetical alternative history. scim.ag/3KMPg85

We are at our future planning meeting at main campus of University 🏰 CVR Genomics CVR Bioinformatics

A warm welcome to our new Principal and Vice-Chancellor, Professor Andy Schofield. Prof Schofield shares a message for the UofG community.  Here’s to this next chapter 💙 #TeamUofG #UofG #Glasgow #University #GlasgowUni #UniversityofGlasgow #GlasgowUniversity #scotland

📢 NEW | The potential of H5N1 viruses to adapt to bovine cells isn’t uniform—it varies throughout their evolution. An international study led by CVR reveals how the potential to cross the species barrier varies during the evolution of H5N1 viruses. biorxiv.org/content/10.110…

Why does the naked mole rat have the longest lifespan and healthspan of any rodent, nearly 40 years? A 30-year long mystery unraveled Science Magazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing

I don’t know who needs to hear this but the CDC is being eviscerated right now. America is not going to have any kind of outbreak response capacity after tonight. Americans’ health data is no longer secure. Say goodbye to federal public health in any capacity.

Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria. doi.org/10.1101/2025.1…