Pleased to announce that my PhD thesis work in Blake Hill Lab on structural mechanisms governing vertebrate FIS1 function is finally out in JBC. sciencedirect.com/science/articl… 🧵a thread

Last call! 🗓️ Dr. Alexander von Appen hosts our June 26 webinar to reveal how the nucleus builds a mechano-protective barrier. Don't miss the opportunity!

Ballistic diffusion fronts in biomolecular condensates: nature.com/articles/s4156…

More than 2700 3′UTRs are highly conserved. These 3′UTRs are essential components in mRNA templates, as their deletion decreases protein activity without changing protein abundance. Highly conserved 3′UTRs help the folding of proteins with long IDRs. biorxiv.org/content/10.110…

Excited to share our preprint on 3'UTR-chaperoned IDR functions!Check it out if you work on a protein with a long IDR and a highly conserved 3'UTR in the mRNA!

How short peptides disassemble tau fibrils in Alzheimer’s disease: nature.com/articles/s4158…

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox | Science science.org/doi/10.1126/sc…

Diffusing protein binders to intrinsically disordered proteins: nature.com/articles/s4158…

Selective association of short tandem repeats with DNA-binding domains and intrinsically disordered regions of transcription factors: Cell Systems cell.com/cell-systems/f…

"The buying of more books than one can read is nothing less than the soul reaching toward infinity." A. Edward Newton

Key West, FL.

Excited to announce the 2026 FASEB Conference on Phase Transitions in Cellular Signaling & Disease! An exciting speaker lineup and >30% of talks will be chosen from submitted abstracts. tinyurl.com/3erxt4tk 📅 Jan 11–15, 2026; 📍 Melbourne, Florida 🌴

Rethinking RNA-binding proteins: Riboregulation challenges prevailing views | Cell Amazing review by HentzeTeam et al.! cell.com/cell/fulltext/…

Accurate prediction of thermoresponsive phase behavior of disordered proteins - Chakravarti - 2025 - Protein Science - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/pr…

A tremendous honor! Thrilled & humbled to receive 2025 Keio Medical Science Prize for launching LLPS #phaseseparation field (= #softmatter + #cellbio) w collaborators esp Hyman Lab. & Congrats to Akiko Iwasaki Prof. Akiko Iwasaki. princeton.edu/news/2025/09/1… #KeioMedicalSciencePrize

Nucleic acid-protein condensates in innate immunity: Molecular Cell cell.com/molecular-cell…

Nuclear Pore Complexes (NPCs) are the gateways to the nucleus, but how can they be both rapid and picky, even for very large cargoes? To answer this question, we built the most detailed data-driven model to date of nucleocytoplasmic transport: pnas.org/doi/10.1073/pn…

Selective RNA sequestration in biomolecular condensates directs cell fate transitions: nature.com/articles/s4158…

🛡️”The Iron Dome”🛡️ Under alcohol stress, a slime mold rapidly retracts into a sclerotia of thousands of hexagonal spherules, sealing so tightly that Dextran-FITC (cyan) can’t enter. Captured by me at the MBL Physiology Course (Gladfelter Lab rotation). #MBL #Microscopy

David Kuster 👀