Alex Wyatt (@researchwyatt) 's Twitter Profile
Alex Wyatt

@researchwyatt

Prostate cancer genomics and ctDNA. Associate Prof for a precision oncology team @VanProstateCtr @UBCmedicine @BCCancer_GSC

ID: 892461041489018880

linkhttps://blogs.ubc.ca/wyattlab/ calendar_today01-08-2017 19:04:28

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Alex Wyatt (@researchwyatt) 's Twitter Profile Photo
Alex Wyatt
@researchwyatt

3 years ago

I'm seeing some conflation of terminology around HRR-related gene mutations and the HRD phenotype in prostate cancer. Here's a slide I use to clarify. It matters because several HRR-related gene alterations (e.g. within ATM) do not appear to result in an HRD mutational signature.

I'm seeing some conflation of terminology around HRR-related gene mutations and the HRD phenotype in prostate cancer. Here's a slide I use to clarify. It matters because several HRR-related gene alterations (e.g. within ATM) do not appear to result in an HRD mutational signature.