Scientists led by Dr. Andrea Reboldi (Reboldi Lab) at UMass Chan Medical School have shown that antigen receptor signaling and cell death resistance control intestinal humoral response zonation. 📙 Study: bit.ly/48wDje6 🎧 Episode: bit.ly/3Pzas05

Katalin Karikó and Drew Weissman – awarded the 2023 #NobelPrize in Physiology or Medicine – discovered that base-modified mRNA can be used to block activation of inflammatory reactions and increase protein production when mRNA is delivered to cells.

Happy Holidays from the Reboldi and Kang Labs!

Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine biorxiv.org/content/10.110… new preprint from the lab. Finalizing experiments for full paper reviews.. Reboldi Lab

Microbiota time! 🦠 #PreprintHub2 w/ Catherine Shelton Mariana Byndloss and 愛理沙 will discuss a #preprint on how microbial FA metabolism expands tuft cells to protect tissues homeostasis during C. difficile infection Vanni Bucci, Ph.D. 🇮🇹🇺🇲🇺🇦 Reboldi Lab 🐭👇 biorxiv.org/content/10.110…

Summer outing for the Labs! #BBQ #StudyCholesterol #EatCholesterol

Congratulations to Victor Ambros and Gary Ruvkun on this momentous achievement! Well deserved. #UMassRNA UMass Chan Medical School

Looking to learn more about modulation of the immune response in tissue by cholesterol & cholesterol metabolites? 🍔🍟🍕🧈 Check out the review Eric V Dang and I wrote for Trends in Immunology sciencedirect.com/science/articl…

Some of our favorite immuno-goblins cell-ebrating the holiday 🎃🍬🧟🧙🏻👻

In Journal of Experimental Medicine, Reboldi Lab Vanni Bucci, Ph.D. 🇮🇹🇺🇲🇺🇦 et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection, providing a pathway thru which host & microbial interactions protect against pathogens hubs.la/Q02ZBWxx0

Toronto-based ImmVue Therapeutics Inc. has licensed a potential UMass Chan Medical School cancer therapeutic for clinical development: direc.to/m4zF This partnership was facilitated by BRIDGE Innovation and Business Development at UMass Chan. Immvue therapeutics CU School of Medicine

Happy Holidays from the Reboldi and Kang Labs 🥂 Cheers to 2025.

.Reboldi Lab, Vanni Bucci, Ph.D. 🇮🇹🇺🇲🇺🇦 et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection. hubs.la/Q036Gplq0 📘 In Host–Microbe Interactions 2025 👉 hubs.la/Q036GsWl0 #KSHumanMicro25 #KSHostMicrobe25