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We are elated! See this spectacular class of future cardiologists & scientists NM Cardiovascular WeAreNUHeart Northwestern Feinberg School of Medicine Northwestern Medicine - to all newly matched cardiology fellows across the U.S., welcome to our community. You inspire us. Find your niche; #MakeADifference 👏🏽👏🏽👏🏽

Nirupama Krishnamurthi Mary Whooley David Schopfer, MD Aziz Nagar Francesca Bartoli-Leonard Elena Aikawa Mandy Turner sasha From LaPenna et al: Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2‐Hit” Murine Model Kyle LaPenna, MD, PhD ZhenLi(Andrew) Sharp Laboratory Ravi Patel Sanjiv J. Shah, MD ahajournals.org/doi/10.1161/JA…

Now out in JAMA Network Open , Art Schuermans and I w/ Alex Reiner Fred Hutch Cancer Center examine the role of clonal hematopoiesis of indeterminate potential (CHIP) 🩸🧬 in future/incident development of heart failure and its subtypes (HFpEF and HFrEF) jamanetwork.com/journals/jaman… 👇 (1/X)

More than 6 million people in the U.S. have heart failure, making it one of the leading causes of hospitalization in the country. Northwestern Feinberg School of Medicine Prof. Sanjiv Shah (Sanjiv J. Shah, MD) explains how his team uses AI in diagnosis, and how it can improve health care: bit.ly/3UUPUn2

What's the mechanism by which cellular adhesion molecules are associated with #AFib and HFpEF? Read insights from the Multi‐Ethnic Study of Atherosclerosis (MESA) about VCAM-1 and ICAM-1. #AHAJournals Graham Peigh, MD, MSc Ravi Patel NM Cardiovascular ahajournals.org/doi/10.1161/JA…

Please help us congratulate Mercedes Carnethon, PhD (Mercedes Carnethon), who has been named the chair of the Department of Preventive Medicine! 👏 spr.ly/6017wDwZF

On Day 1 at #ACC24, Northwestern Medicine Bluhm Cardiovascular Institute resident, Kasen Culler, MD (Kasen Culler), presents his poster on the effect of #MetabolomicProfiling on #MyoInositol #metabolism in early #HeartFailure.

Cardiology Grand Rounds NM Cardiovascular - recap #LBCT #ACC2024 - outstanding fellow led discussions. Will practice change? New hypotheses? PLUS 2 announcements: Jess Quaggin-Smith - Bonow research proposal award winner & WeAreNUHeart won American Heart Association fellow research award grant👏🏽

Amazing job by our fellow presenters and faculty moderators this morning recapping top line results from American College of Cardiology! Ravi Patel Alana A. Lewis, MD NM Cardiovascular Marysa Leya

Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambers and increases in volume of right-sided chambers but no change in RV systolic function compared with sham. ja.ma/3Q2LuHC

Feinberg investigators have been selected to lead a $15 million American Heart Association research initiative studying the role of #inflammation in #HeartDisease. spr.ly/6019bcpfF

People can experience different outcomes from the same #HeartFailure therapies, which is why investigators are studying subgroups who may respond to an atrial shunt, a device that transfers blood from the left to right side of the heart: bit.ly/4diRUMP JAMA Cardiology

Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant - PubMed pubmed.ncbi.nlm.nih.gov/39034892/

Mavacamten was associated with reductions in biomarkers of cardiac wall stress and injury, with no sustained reductions in LVEF observed in patients with HFpEF and LVEF of 60% or greater. ja.ma/4dljU0X #HFSA2024

REBALANCE-HF trial: While splanchnic ablation for volume management (SAVM) did not reduce PCWP in HFpEF overall, subgroup analysis suggests benefits in patients with preserved cardiac output during exercise and less severe diastolic dysfunction. ja.ma/3TSNYKv

In a large cohort of African-American women, the ICAM1 missense variant rs5491 (p.Lys56Met) was specifically associated with #HFpEF hospitalization among individuals starting at the age of 70 years. bit.ly/4ePcDaP #JACCHF #HeartFailure #cvGenetics

In this #JACCBTS analysis, a common missense variant of ICAM-1 among African American individuals that has been associated with #HFpEF appears to be associated with circulating inflammatory proteins. Get the details: bit.ly/3TVqwMZ

Matthew Feinstein joins us from Northwestern Feinberg School of Medicine NM Cardiovascular to discuss the complex immune system modifiers of cardiovascular disease. Wow. My head is spinning. So much to discuss with him today! Clyde Yancy, MD, MSc Sanjiv J. Shah, MD Jane Wilcox, MD, MSc Sadiya Khan have compelling reasons to be

ANOTHER round of Top Site-Coordinators who have proven their dedication to the CV ecosystem through their impressive work in HF trials. Join us in congratulating all of our Site-Based Research award winners! 🎉 #AHA #AHA24 hfcollaboratory.com/awards

To better predict risks for #HeartFailure, investigators are studying how byproducts of metabolism may provide insight into risks and support earlier interventions: go.nature.com/3AcnuNq Scientific Reports #CardioTwitter