Rapé Lab (@rapelab) 's Twitter Profile
Rapé Lab

@rapelab

molecular mechanisms of cell fate specification in development and disease; molecular glues and induced protein degradation as new therapeutic options

ID: 3002756670

linkhttp://mcb.berkeley.edu/labs/rape/ calendar_today30-01-2015 04:04:28

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Rapé Lab
@rapelab

9 months ago

Excited to report our discovery of an important component of the oxidative stress response, the E3 ligase TRIP12. It acts as a chain elongation factor that amplifies CUL3-KEAP1 activity to drive NRF2 degradation as cells recover from stress. biorxiv.org/content/10.110…