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Our 6-yr efforts is finally published on Nature Communications! We discover a neural pathway that regulates the glymphatic system. Its deficit in aging and dementia may result in the pathology. This suggests new targets for diagnosis and treatment. nature.com/articles/s4146…

I’m at the OHBM in Brisbane and I'm competing in the "Brain Art" contest! Check out my entries (#1.1 and #2.6) here: sites.google.com/view/ohbm-brai…. If you want to boost my chances of winning, please vote for each category here: docs.google.com/forms/d/e/1FAI… Thanks!

direct.mit.edu/imag/article/d…

Happy to be part of the upcoming SPIE conference - Emerging Topics in Artificial Intelligence (ETAI) 2025 . Grateful for the extraordinary efforts of the organizers, making things happen! And beautifully! Join us in San Diego! spie.org/opn/conference…

Proud of our scholars, their dedication to science, resilience and grace! Wishing lots of success to Profesor Merenstein! dukeuncadrc.org/news/rec-schol…

biorxiv.org/content/10.110…

What do you see when you stare at this grid of line segments: a series of rectangles, or a series of circles? The way you perceive this optical illusion may tie back to the visual environment that surrounds you, a recent preprint suggests. scim.ag/40e6PCU

Does mental stress affect our mitochondria? In this new paper, we asked if 5 minutes of mental stress (public speaking) changed the amount of cell-free mitochondrial DNA (cf-mtDNA) Absolute saliva cf-mtDNA levels increased on average by 280% after mental stress! 🧵

new preprint from our lab: Modular striatal dynamics and reciprocal inhibition orchestrate skilled action sequencing. Using high-resolution kinematics tracking and neural recordings in mice performing a water-reaching task, we found spatially distributed modules of striatal

Our new paper presents a #PhotonCountingCT scanner for dynamic small animal perfusion imaging. Deep learning enables fast 5D imaging. #DeepLearning Photon-counting micro-CT scanner for deep learning-enabled small animal perfusion imaging doi.org/10.1088/1361-6…

If you don’t have time to take a walk, then you don’t have time to do science. Charles Darwin would take two walks every day on his "thinking path", not as a break from science, but as a crucial part of it.

“Doubt is a tool”🧠😁 #creativity

“Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction” by Sudipta Bar et al. Nature Metabolism dx.doi.org/10.1038/s42255…

Our featured article for August is this Review, in which Raquel Taddei and Karen Duff consider the importance and mechanisms of synapse resilience and vulnerability in dementia. You can read it in full for free here: rdcu.be/eurPp Duff Lab

This study observed small but important differences in rates of AD, up to 20% greater incidence in several regions compared with the Mid-Atlantic. How to use this data to devise strategies that mitigate the impact of dementia on vulnerable populations?jamanetwork.com/journals/jaman…

Very excited to share the results of this collaborative work in young adults with spina bifida. APOE4 carriers showed smaller left amygdala volumes —suggesting early neurodegeneration risk. Can MRI help identify vulnerable SB subgroups? #APOE4 #MRI doi.org/10.1002/cns3.7…

“An inventor looks for trouble” 😁#creativity

nature.com/articles/s4358…

What a perfect day feels like!

cell.com/cell-reports/f…