IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases nature.com/articles/s4158…

Congrats to Ashley Moffett and team on this exciting new paper. Human uterine natural killer cells regulate differentiation of extravi... sciencedirect.com/science/articl…

🔬 Scientists at Cambridge Pathology Cambridge Reproduction have grown ‘mini-placentas’ in the lab and used them to see how the placenta develops and interacts with the womb. 🤰 The findings could help scientists better understand - and potentially treat - pre-eclampsia.

🌟NEW in Nature Medicine: Excited to see this insightful trial report on CAR-#NKcells in patients with #lymphoma & #leukemia out! LOTS to dig into! Congrats to Katy Rezvani, M.D., Ph.D @Yl668Li Rafet Hind Rafei May Daher & all authors! MD Anderson Cancer Center #CARTcells nature.com/articles/s4159…

What happens when an NK cell, T cell and macrophage walk into an hgsc tumour? #ovariancancer #spatialbiology #nkcells frontiersin.org/articles/10.33… #ovariancancer

Senior postdoc job available in our department to study the structural basis for T cell recognition of HLA-E. Lead by the wonderful ⁦Geraldine Gillespie⁩ at ⁦University of Oxford⁩ 👇 jobs.ac.uk/job/DFU916/sen…

We are hiring another Pediatric Stem Cell Transplant/Cellular Therapy Physician University of Wisconsin Department of Pediatrics UW Health Kids UW Health | Carbone Cancer Center Come join our expanding and talented team in Madison! #BMT #GVHD #CARTcells #NKcells #VSTs jobs.wisc.edu/jobs/pediatric…

New pre-print from us online at bioRxiv we make use of human uterus and bone marrow transplantation to determine functional characteristics of uterine immune system replenishment #nkcells #tcells #tissueimmunology tinyurl.com/mrx7u4pu

So excited to see this *officially* published!! Take a look at the first "Burrack Lab" publication! Lots more in the works!

Terrifying graph showing how warm the oceans have been this year, compared to what we’re used to (grey lines). No wonder we’re seeing corals overheating, bleaching and dying right around the planet, from the Caribbean to the Maldives to Australia. #ClimateCrisis

Did you know that all articles in our Biographical Memoirs are free to access online? Explore the stories behind some of the greatest scientists who've ever lived: ow.ly/wGqC50Rm9La #BioMems #HistSci

Cryopreservation protocols optimized for T cells kill ~75% of NK cells w/in 24 h of thaw due to leakage of GzmB from vesicles. This is prevented by IL15/IL-18 pretreatment to ⬆️antiapoptotic genes & deplete gzmB containing granules [Berjis & Sheppard] nature.com/articles/s4146…

Just published in Cell Reports #OpenAccess. We show that the palmitoyl transferase ZDHHC20 mediates metastasis of pancreatic cancer in vivo. cell.com/cell-reports/f…

cellPLATO software for measurement and classification of cell behaviors based on cell morphology and motility, shows IL-15 increases migration behavior plasticity & different integrin ligands induce distinct NK cell migration forms EM Mace Michael Shannon doi.org/10.1242/jcs.26…

Altered NK–DC–CD8+ T cell cross-talk in aged tumors impairs T cell priming by cDC1 & promotes age-associated dysfunctional T cells, such that aged are unable to benefit from therapeutic tumor vaccination Nature Immunology Debattama Sen Alex C.Y. Chen nature.com/articles/s4159…

If you're looking for a PhD, & passionate about #helminths & #mucosal #immunity, please apply! This project in Edinburgh will investigate intestinal/lung #inflammation, tissue damage & repair during murine #schistosome infection (deadline 10th August) 🪱🤓findaphd.com/phds/project/m…

Come and join the Lydia Becker Institute, seeking a lecturer/senior lecturer. jobs.manchester.ac.uk/Job/JobDetail?…

Dr Jess Wade is awarded the Royal Society Rosalind Franklin Award and Lecture for her achievements in functional materials and her outstanding project which will support early career women scientists to pursue academic careers in materials sciences. #RSMedals

Let me introduce: InstanSeg 🦠🔬💻👩‍🔬 This *would* have been a short thread about Thibaut Goldsborough’s PhD work… but he solved too many problems. Now it's a long thread about 2 preprints, a whole new approach to cell segmentation & #opensource software to make it easy to use