🏃‍♂️🏋️May is #NationalPhysicalFitnessMonth ! This insightful review by Egan et all shows how aerobic fitness and skeletal muscle strength can delay the onset of lifestyle-related chronic diseases

doi/full/10.1152/physrev.00054.2021

#Exercise #Metabolism #Aerobic

Interesting study from Physiological Genomics

We recommend this review from @physiol_rev Evolution of the diagnostic value of “the sugar of the blood”: hitting the sweet spot to identify alterations in glucose dynamics by Magkos et al
doi.org/10.1152/physre…

#diabetes #obesity

Recommended Reading from Physiological Reviews for #StrokeAwarenessMonth 🧠

Fluid transport in the #brain
doi.org/10.1152/physre…

#ExtracellularMatrix #CerebrospinalFluid
#GlymphaticSystem

🆕Adepu et al present working models illustrating the possible importance of interactions between #myoglobin , gases, and small molecule metabolites in regulation of #CellSignaling and #bioenergetics

journals.physiology.org/doi/abs/10.115…

🚺Exciting news!

APS is delighted to share its Women's Health Research Initiative! By understanding women's health issues and improving treatment options, we can improve the lives of women everywhere! ♀️

Podcast *coming soon* on this important Review!

Physiological Basis for #Xenotransplantation from Genetically-Modified Pigs to Humans
Peterson et al. ow.ly/jksb50RKwbJ

➡️This fascinating blog post parallels research from Furrer et al: The Molecular Athlete: Exercise Physiology From Mechanisms To Medals 🥇

journals.physiology.org/doi/full/10.11…

#Exercise #Athlete

The Physiological Reviews Podcast 🎧Dr. Kheradmand interviews Dr. Harrod about community-acquired bacterial coinfections & #COVID19 , including linkages between carriage, viral infection & secondary infections, as well as pathophysiology of fungal coinfections ow.ly/poNi50RHl12

🆕 Wilkerson et al. review the biosynthesis and degradation pathways that maintain #ceramide levels in normal #physiology and discuss how the loss of ceramide homeostasis drives #cardiometabolic pathologies.
ow.ly/cfM850REuZQ

#Diabetes #Lipotoxicity

.AJP-Gastrointestinal and Liver Physiology Podcast ⚠️ Authors Jia Liu & Bin Feng highlight research titled 'Morphological, molecular, & functional characterization of mouse glutamatergic #MyentericNeurons '
🎧ow.ly/NNXZ50REthO
📃ow.ly/ZiGn50REtll
#Glutamate #VesicularGlutamateTransporter #CalciumImaging

It’s #NationalWomensHealthWeek ! #ISpyPhysiology blog explains:
• Why women have a harder time losing weight ow.ly/ctBv50Rmzy3
• How #HeartDisease differs in women and men ow.ly/INQ450Rmzy5
• Why air pollution affects more women than men ow.ly/6BHZ50Rmzy2

Growing evidence implicates #glucagon as more than a #glucose liberator. Glucagon plays key regulatory roles in hepatic amino acid & #KetoneBody metabolism, indicating broader glucagon signaling consequences for metabolic homeostasis mediated by the #liver ow.ly/fgE550RBKzq

Physiological Reviews Article Collections help readers find content faster. This week we're featuring the topic collection on #cancer ➡️ ow.ly/4lwq50RyFJi

The May issue of #TPhysMag is out! Read about the new APS president, advances in #SickleCell disease, how to improve the postdoc experience and more: ow.ly/IWgY50RvSqz

Interesting research in AJP-Lung Cellular and Molecular Physiology

We recommend reading this Review in Physiological Reviews
➡️ Contribution of adaptive immunity to human #COPD and experimental models of emphysema
doi.org/10.1152/physre…

#autoimmunity #emphysema

Friday is a great day to catch up on the latest episodes of The Physiological Reviews Podcast

Community-Acquired #BacterialCoinfections and #COVID
🎧 ow.ly/fWNH50RvMt2

#SexDifferences in Blood Pressure Regulation and #Hypertension
🎧 ow.ly/KRyt50RvMt4

#SARSCoV2 #SABV

Interesting AJP-Heart and Circ Review on pathobiology of #PulmonaryHypertension in #HFpEF 👍

Recommended Review in Physiological Reviews
👉Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling
doi.org/10.1152/physre…

I highly recommend this review- great job jennifer van eyk & team!

Review by Karpov et al. @cedarssinai encapsulates the evolution, current technologies, and future perspectives of #proteomic -based #MassSpectrometry as it applies to the study of the #heart ow.ly/yISc50RsSRy

#Proteomics #Cardiac #Cardiovascular

Is the prevalence of bacterial coinfections in critically-ill hospitalized #COVID patients being accurately reported? Listen to the latest episode of The Physiological Reviews Podcast to find out: ow.ly/fyir50RqKxT