Excited to share our study published by the BMJ today, which finds a gradual increase in the risk of covid-19 infection from 90 days after receiving a second dose of the Pfizer-BioNTech vaccine. The BMJ 1/8 bmj.com/content/375/bm…

Measure success by the joy you get from your work and that what you publish is true!

Discover immunotherapy biomarkers from single-cell cytometry data: cell.com/patterns/fullt… A short preview article we wrote to highlight a recent publication and briefly summary the relevant literature.

A common way to ruin your project is to skip doing a series of pilots before the big expensive experiment. Pilots help you work out the problems and prevent the creation of impossible-to-analyze datasets. Published papers often don't discuss pilots, encouraging us to do the same.

We are very excited to release our Tres framework to evaluate T-cell anti-tumor efficacy, and FIBP as a candidate immunotherapy target. The paper is published on Nature Medicine: nature.com/articles/s4159… The Tres server is available at: resilience.ccr.cancer.gov

Gene signatures associated with T cell resilience to tumor-derived immunosuppressive signals predict responses to immune checkpoint inhibitors and adoptive cell therapy, and identify FIBP as a negative regulator of T cell activity Peng Jiang National Cancer Institute nature.com/articles/s4159…

Thank you to Cancer Discovery Cancer Discovery for highlighting our recent work. doi.org/10.1158/2159-8…

Dear All, My Lab has a postdoc position available in Bioinformatics and Cancer Data Sciences. I would sincerely appreciate it if you can forward the following advertisement to young talents: ccr.cancer.gov/careers/post-d…

Dear All, my branch Chief Eytan @NCIEytanRuppin and Chief of Pathology @NCIKenAldape, and I are co-recruiting a wet-lab Postdoc on Cancer Spatial and Functional Genomics.

Why high tumor mutation burden is only predictive of immunotherapy response in some cancer types? We answer this question in our latest publication below and are excited to share it here. A🧵of 🏄‍♀️ below. aacrjournals.org/cancerres/arti…

NEW content online! Big data in basic and translational cancer research dlvr.it/SXpZtB

Our review paper on Big data applications in Cancer is online at Nature Reviews Cancer Nature Reviews Cancer: rdcu.be/cUZSR. reflecting joint insights from our colleagues (@NCIEytanRuppin @NCIKenAldape Sridhar Hannenhalli Cenk Sahinalp & Team Sanju Sinha)

Advertise a half-day symposium on Gene & Cell Therapy by the Chinese Biopharm Association.

Interested in aging and cancer. I did a year of literature survey on this. Here is my list of 20 key open questions and challenges to better understand the interplay between aging and cancer. A thread 🧵👇

We have released the SpaCET package for cell lineage deconvolution and cell-cell interaction inference in Tumor Spatial Transcriptomics: nature.com/articles/s4146… Welcome to try our package: github.com/data2intellige… Congratulations to Dr. Beibei Ru and Dr. Jinlin Huang.

Recently published: Beibei RU Peng Jiang @NCIEytanRuppin develop Spatial Cellular Estimator for Tumors (SpaCET) to infer cell types and ligand-receptor interactions from #SpatialTranscriptomics data in cancer #CancerResearch Cancer at Nature Portfolio doi.org/10.1038/s41467…

With a mixed bag of emotions - nervousness, excitement, fear & determination, I am announcing the start of my lab at Sanford Burnham Prebys, San Diego. Our focus will be to develop new preventative therapies for cancer using machine learning.

Our paper "A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels" has been accepted at the IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology! linkedin.com/posts/jacoblub…

Our Cell paper is online (doi.org/10.1016/j.cell…)! We present the CIDE framework, broadly applicable to cancer research and oncology. Also, we highlight AOAH as a promising new immunotherapy.

A new Cell paper is online from brilliant CDSLers! This paper presents the Cancer Immunology Data Engine (CIDE) framework, broadly applicable to #CancerResearch and #Oncology. AOAH is featured as a promising new #Immunotherapy. doi.org/10.1016/j.cell…